With the increasing demand for green and efficient energy storage devices, advanced technologies for clean energy conversion have attracted close attention from researchers. Fuel cells with environmental friendliness and high energy conversion efficiency are promising alternatives to traditional energy sources. However, Pt catalysts with high commercialization degrees in the industrial catalysis field have some problems, such as high cost, poor stability and weak anti-toxicity ability, which limits the further development of fuel cells. The development of non-Pt oxygen reduction reaction (ORR) catalysts with abundant reserves, low cost and excellent performance is an effective way to improve the efficiency of fuel cells. In this paper, based on the research results at home and abroad in recent years, various types of non-Pt system ORR catalysts, including non-precious metal and non-metal catalysts, are systematically introduced. The advantages, disadvantages and modification strategies of various catalysts are summarized, and challenges and prospects for the development of ORR electrocatalysts are put forward.