Issn: CN 22-1128/O6
Director:Chinese Academy of Sciences
Host:Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
This review consists of two parts. The first part presented here emphasizes the synthesis,chain structure, doping, morphological and crystal structure of polyaniline. The secondpart will be issued on the next number this Journal with the emphasis on the electronicphenomena, conducting mechanism, properties and applications of polyaniline.
Recent advances of polyaniline in electronic phenomena, conducting mechanism, properties and applications are reviewed.
Phaseselective gelation of mixed un-miscible solvents is of great importance considering its applications in purification and separation, particularly in the recovery of spilled oil and in the purification of water. Gelators with phase-selective gelation properties could be polymers, micro- nano-particles or low-molecular mass gelators(LMMGs). Compared with former two kinds of gelators, gelation using LMMGs as gelators is always reversible. Such reversibility could add additional advantages to practical applications of the gel systems. Progress in the studies of LMMGs with phase-selective gelation properties is reviewed according to the structures of the relevant gelators. Furthermore, prospectives of the studies and the potential applications of the phaseselective gelation phenomenon are also presented.
The anti-tumor effects of the polymer-paclitaxel conjugate micelles and free paclitaxel on H22 liver cancer bearing mice were evaluated. After 10 days drug administration, the tumor volume inhibition rates(VIR) of free paclitaxel group, polymer-paclitaxel conjugate micelles group at doses of 3 mg/kg, and the micelles group at doses of 6 mg/kg are 22%, 49%, and 67%, respectively. In addition, the tumor weight inhibition rates (WIR) are 29%, 45%, and 47%, respectively. Protein expression results show that paclitaxel micelles group has higher expression of p53 and lower expression of bcl-2. All these results indicate that the anti-tumor effect of polymer-paclitaxel conjugate micelles is stronger than free paclitaxel.