Study on Biologically Active Schiff Base Complexes of Formylformic Acid with Thiosemicarbazide

Chinese Journal of Applied Chemistry ›› 1994, Vol. 0 ›› Issue (5): 45-48.

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Study on Biologically Active Schiff Base Complexes of Formylformic Acid with Thiosemicarbazide

Tian Junlian, Bi Siwei, Gao Enqing, Li Yantuan, Li Guizhi, Liu Shuxiang

Department of Chemistry, Qufu Normal University, Qufu 273165

Received:1994-01-12 Revised:1994-04-07 Published:1994-10-10 Online:1994-10-10

Abstract

Abstract: Some bivalent metal ion complexes of Schiff bases derived from formylformic acid and thiosemicarbazide were synthesized.The composition of the complexes were determined as M(HFFTSC)₂·nH₂O(M=Co(Ⅱ),Ni(Ⅱ),n=2;M=Zn(Ⅱ),n=1;M=Mn(⒓),Pb(1),n=0) and Cu(FFTSC)·H₂O based on the elemental analysis data and molar conductance measurements.The IR results showed that the ligand behaves as in a tridentate manner.The antibacterial activity of the complexes were examined.

Key words: formylformic acid thiosemicarbazide Schiff base, transition element, complex, antibacterial activity

Tian Junlian, Bi Siwei, Gao Enqing, Li Yantuan, Li Guizhi, Liu Shuxiang. Study on Biologically Active Schiff Base Complexes of Formylformic Acid with Thiosemicarbazide[J]. Chinese Journal of Applied Chemistry, 1994, 0(5): 45-48.

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Study on Biologically Active Schiff Base Complexes of Formylformic Acid with Thiosemicarbazide

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