Chinese Journal of Applied Chemistry ›› 1991, Vol. 0 ›› Issue (1): 38-41.

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SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF 3,4-DIHYDRO-ISOBENZOPYRANO[3,4-b]PYRIDONE

Wang Jinjun1, Han Guangfan2, Jiang Guiji3   

  1. 1. Department of Fine Chemical Technology, Jilin Chemical Engineering College, Jilin 132022;
    2. Department of Medical Laboratory, Jilin Medical In Stitute;
    3. Department of Chemistry, Yanbian University
  • Received:1990-01-12 Revised:1990-05-22 Published:1991-02-10 Online:1991-02-10

Abstract: Title compounds (3 and 4) have been synthesized by Aldol condensation of α,β-unsatu-rated-ketones (2) with cyanoacetamides respectively.Some of the compounds show asignificant anti-inflammatory activity.

Key words: dihydroisobenzopyran, synthesis, drug, anti-inflammatory activity