Chinese Journal of Applied Chemistry

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Electrochemical Behavior and Determination of Calcium Dobesilate at Graphene Modified Glassy Carbon Electrode

ZHANG Ya1*, DU Fangyan1, ZHENG Jianbin2   

  1. (1.Department of Chemistry and Chemical Engineering,Yulin College,Yulin  719000,China;
    2.Institute of Analytical Science,Northwest University,Xi′an 710069,China)
  • Received:2013-09-24 Revised:2013-11-12 Online:2014-07-10 Published:2014-07-10

Abstract: A graphene modified glassy carbon electrode(GN/GCE) was prepared. The electrochemical behavior of calcium dobesilate on the modified electrode was investigated in 0.05 mol/L H2SO4 by cyclic voltammetry. The GN/GCE shows an obvious electrocatalytic activity toward the redox reaction of calcium dobesilate and a new method for the determination of calcium dobesilate is established. On differential pulse voltammetry curves, a linear dependence of oxidation current versus calcium dobesilate concentration is obtained in the range of 2.0×10-9~1.2×10-6 mol/L, with a detection limit of 1.0×10-9 mol/L(S/N=3). The proposed method was applied to determine calcium dobesilate in capsule. The modified electrode shows excellent stability and reproducibility.

Key words: calcium dobesilate, graphene, modified electrode, electrocatalysis

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