Chinese Journal of Applied Chemistry

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Determination of Jatrorrhizine Hydrochloride by Core-shell CdTe/CdS Quantum Dots with Fluorescence Quenching Method

YIN Pengfei, GONG Huiping, LIU Zhengqing, WANG Xiaodan, LI Pingping, HE Youqiu*   

  1. (School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715)
  • Received:2011-04-19 Revised:2011-06-29 Online:2012-03-10 Published:2012-03-10
  • Contact: Youqiu

Abstract: The mercaptoacetic acid(TGA) stabilized core-shell CdTe/CdS quantum dots(TGA-CdTe/CdS QDs) were synthesized using as stabilizer. A new method for the determination of jatrorrhizine hydrochloride has been developed based on the quenching of the fluorescence of TGA-CdTe/CdS QDs at excitation wavelength of 340 nm. The paper utilized fluorescence spectrometry and ultraviolet-visible(UV-Vis) absorption spectra to study the interaction between TGA-CdTe/CdS QDs and jatrorrhizine hydrochloride(JH). Under optimized conditions, in which at the pH value is 7.4 using tris-HCl buffer solution, the quenched fluorescence intensity of TGA-CdTe/CdS QDs was linearly proportional with a correlation coefficient r=0.9991, and the limits of detection were in the range of 0.011~10 mg/L and the detection limit for JH(3σ) was 3.3×10-3 mg/L. JH could be conveniently and quantitatively detemined using this new method.

Key words: Jatrorrhizine hydrochloride, core-shell CdTe/CdS quantum dots, UV-Vis, fluorescence quenching

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