β-环糊精及衍生物与β-胡萝卜素包合物性质

doi:10.11944/j.issn.1000-0518.2016.07.150352

摘要/Abstract

摘要：

为了改善β-胡萝卜素的理化性质,如水溶性和光稳定性等,分别制备了β-胡萝卜素与β-环糊精、2-羟丙基-β-环糊精、磺丁基醚-β-环糊精的固体包合物。利用紫外-可见吸收光谱、傅里叶红外转换光谱和核磁技术对β-胡萝卜素与环糊精及其衍生物的包合物进行研究。通过对包合物理化性质的研究发现:通过β-环糊精、2-羟丙基-β-环糊精、磺丁基醚-β-环糊精包合后的β-胡萝卜素的理化性质,包括热稳定性、光稳定性和抗氧化性,均有显著提高;经2-羟丙基-β-环糊精和磺丁基醚-β-环糊精包合后,β-胡萝卜素分别增溶12倍和18倍。

关键词: β-胡萝卜素, 环糊精, 水溶性, 包合物, 稳定性

Abstract:

The solid inclusion complexes of β-carotene with β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin were prepared in order to improve physicochemical properties of β-carotene, such as solubility and stability. The inclusion complexes of β-carotene with β-cyclodextrin and its derivatives were characterized by UV-Vis absorption spectroscopy, Fourier-transform infrared spectroscopy and ¹H NMR spectroscopy. The physicochemical properties of inclusion complexes indicate that the heat stability, light stability and antioxidant activity of β-carotene are evidently improved by the formation of inclusion complexes of β-carotene with β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin, respectively. The solubility of β-carotene increases 12 times and 18 times by the formation of inclusion complexes of β-carotene with 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin, respectively.

Key words: β-carotene, cyclodextrins, inclusion complex

周叶红, 马学文, 梁文婷, 董川, 双少敏. β-环糊精及衍生物与β-胡萝卜素包合物性质[J]. 应用化学, 2016, 33(7): 827-833.

ZHOU Yehong, MA Xuewen, LIANG Wenting, DONG Chuan, SHUANG Shaomin. Preparation and Physicochemical Properties of the Inclusion Complexes of β-Carotene with β-Cyclodextrin and Its Derivatives[J]. Chinese Journal of Applied Chemistry, 2016, 33(7): 827-833.

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