溴酸钠和氯化铁为助催化剂2,2,6,6-四甲基-N-氧化哌啶催化醇的氧化

doi:10.11944/j.issn.1000-0518.2015.06.140331

摘要/Abstract

摘要：

建立了溴酸钠和氯化铁为助催化剂2,2,6,6-四甲基-N-氧化哌啶(NaBrO₃-FeCl₃-TEMPO)新型催化体系,以苯甲醇的氧化为研究对象,得出各成分与底物的最佳物质的量比为:2%TEMPO、35%NaBrO₃、3.7%H₂SO₄、2%FeCl₃·6H₂O。该体系在室温下可有效实现芳香醇、脂肪醇及杂环醇的氧化,收率高(99%)、选择性强(99%),在无氧条件下,仍表现出较好的催化活性。

关键词: 四甲基-N-氧化哌啶, 溴酸钠, 醇, 氧化

Abstract:

A 2,2,6,6-tetramethyl-1-piperidinyloxy catalytic system with sodium bromate and ferric chloride as accelorators(NaBrO₃-FeCl₃-TEMPO) was developed for efficient oxidation of alcohols. Taking example for benzyl alcohol, the molar ratios of TEMPO, NaBrO₃, H₂SO₄, FeCl₃·6H₂O relative to the substrate are optimized at 2%, 35%, 3.7% and 2%, respectively. Aromatic alcohol, aliphatic alcohol and heterocyclic alcohol can be effectively oxidized to the corresponding carbonyl compounds with high yields up to 99% and selectivity up to 99% at room temperature even under anaerobic conditions.

Key words: tetramethyl-piperidinyloxy, sodium bromate, alcohol, oxidation

中图分类号:

褚朝森, 王晓丽, 胡玉涛, 闫秀美, 王政. 溴酸钠和氯化铁为助催化剂2,2,6,6-四甲基-N-氧化哌啶催化醇的氧化[J]. 应用化学, 2015, 32(6): 666-670.

CHU Chaosen, WANG Xiaoli, HU Yutao, YAN Xiumei, WANG Zheng. Catalyzed Oxidation of Alcohols by 2,2,6,6-Tetramethyl-1-iperidinyloxy with Sodium Bromate and Ferric Chloride as Accelorators[J]. Chinese Journal of Applied Chemistry, 2015, 32(6): 666-670.

参考文献

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