中华医学超声杂志

应用化学 ›› 2011, Vol. 28 ›› Issue (05): 590-596.DOI: 10.3724/SP.J.1095.2011.00536

• 研究论文 • 上一篇    下一篇

聚氨基黑10B修饰电极检测维生素B6

王春燕1,2,3,田坚2*,由天艳1*   

  1. (1.中国科学院长春应用化学研究所，电分析化学国家重点实验室 长春 130022；
    2.长春理工大学生命科学技术学院 长春 130021；3.吉林工程技术师范学院食品工程学院 长春)
  • 收稿日期:2010-09-14 修回日期:2010-11-05 出版日期:2011-05-10 发布日期:2011-05-10
  • 通讯作者: 由天艳，研究员; Tel/Fax:0431-85626850; E-mail:youty@ciac.jl.cn; 研究方向：纳米材料的合成及毛细管电泳电化学检测联用技术
  • 基金资助:
    国家自然科学基金（20875085）资助项目

Determination of Vitamin B6 on a Poly(amino black 10B) Modified Electrode

WANG Chunyan1,2,3, TIAN Jian2*, YOU Tianyan1*   

  1. (1.State Key Laboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,
    Chinese Academy of Sciences,Changchun 130022;
    2.School of Life Science and Technology,Changchun University of Science and Technology,Changchun 130021;
    3.School of Food Engineering,Jilin Teacher′s Institute of Engineering and Technology,Changchun)
  • Received:2010-09-14 Revised:2010-11-05 Published:2011-05-10 Online:2011-05-10
  • Contact: you

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摘要：

采用电化学聚合的方法将氨基黑10B染料分子修饰到玻碳电极表面，制备了聚氨基黑10B修饰电极，其稳定性和重复性较好。 该修饰电极对维生素B6（VB6）的氧化有明显的电催化作用，VB6的氧化峰电位负移，电流显著增加。 利用微分脉冲伏安和安培检测技术对VB6进行了定量检测，检测限均可达到0.05 μmol/L，与已报道的修饰电极比较，是目前最低的。 将该修饰电极用于不同药物制剂中VB6浓度的测定，操作方便、快速，方法灵敏，准确度高。

关键词: 维生素B6, 修饰电极, 氨基黑10B, 电催化, 安培检测

Abstract:

A poly(amino black 10B) modified glassy carbon electrode, prepared by electrochemical polymerization, was developed for the direct determination of vitamin B6. The polymer thickness can be controlled by potential circles. The modified electrode shows obvious electrocatalytic activity toward the oxidation of vitamin B6, since it decreases the oxidation overpotential as well as greatly enhances the oxidation peak current of vitamin B6. Differential pulse voltammetry and amperometric detection methods were utilized for the measurement of vitamin B6. The method is very sensitive and simple, and the detection limit is 0.05 μmol/L. Compared with other known modified electrodes, the poly(amino black 10B) modified electrode possesses many advantages such as low detection limit, fast response, good repeatability, low cost and simplicity. The practical application of this modified electrode was demonstrated with vitamin B6 drugs.

Key words: Vitamin B6, Modified electrode, Amino Black 10B, Electrocatalysis, Amperometric detection

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