双核铜(Ⅱ)配合物{[Cu(Phen)(Nap)2]2·(EtOH)2·(H2O)2}(Phen=1,10-菲咯啉,Nap=1-萘甲酸,EtOH=乙醇)的合成、晶体结构及性质

doi:10.11944/j.issn.1000-0518.2016.08.150402

摘要/Abstract

摘要：

合成了一种新型的配合物{[Cu(Phen)(Nap)₂]₂·(EtOH)₂·(H₂O)₂}(Phen=1,10-菲咯啉,Nap=1-萘甲酸,EtOH=乙醇)。通过元素分析、红外光谱、热重等测试技术对其进行了表征,同时用X射线单晶衍射确定了其晶体结构,其配合物为双核铜结构。利用循环伏安法和发射光谱研究了该配合物的电化学和发光性能;采用紫外光谱和荧光光谱法研究了配合物与小牛胸腺DNA(ct-DNA)的相互作用。结果表明,配合物为不可逆氧化还原过程,其荧光发射光谱为416 nm,与小牛胸腺DNA(ct-DNA)以沟面结合方式相互作用,配合物结合常数K_b1=4.68×10³ L/mol。

关键词: 双核铜(Ⅱ)配合物, 合成, 晶体结构, DNA, 电化学性能

Abstract:

A new complex [Cu(Phen)(Nap)₂]₂·(EtOH)₂·(H₂O)₂(Phen=1,10-phenanthroline; Nap=1-naphthoic acid; EtOH=ethyl alcohol) was synthesized. The compound was characterized by elemental analysis, FTIR, TG-DTG, single crystal X-ray diffraction. The complex is dinuclear copper(Ⅱ) structure. The electrochemical and luminescent properties of the complex was studied by cyclic voltammetry and emission spectrum. The interactions of the complex with calf thymus DNA(ct-DNA) has been studied by UV and fluorescence spectroscopy. The results show that the copper(Ⅱ) complex shows irreversible redox process, and possesses a fluorescent emission band at 416 nm, and this copper(Ⅱ) complex binds to ct-DNA in groove binding and its intrinsic binding constant K_b is 4.68×10³ L/mol.

Key words: dinuclear copper(Ⅱ) complex, synthesis, crystal structure, DNA, electrochemical performance

朱小明, 冯泳兰, 张复兴, 庾江喜, 蒋伍玖, 欧亚平, 邝代治. 双核铜(Ⅱ)配合物{[Cu(Phen)(Nap)₂]₂·(EtOH)₂·(H₂O)₂}(Phen=1,10-菲咯啉,Nap=1-萘甲酸,EtOH=乙醇)的合成、晶体结构及性质[J]. 应用化学, 2016, 33(8): 932-938.

ZHU Xiaoming, FENG Yonglan, ZHANG Fuxing, YU Jiangxi, JIANG Wujiu, OU Yaping, KUANG Daizhi. Synthesis, Crystal Structure and Properties of Dinuclear Copper(Ⅱ) Complex {[Cu(Phen)(Nap)₂]₂·(EtOH)₂·(H₂O)₂} (Phen=1,10-Phenanthroline; Nap=1-Naphthoic Acid; EtOH=Ethyl Alcohol)[J]. Chinese Journal of Applied Chemistry, 2016, 33(8): 932-938.

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双核铜(Ⅱ)配合物{[Cu(Phen)(Nap)₂]₂·(EtOH)₂·(H₂O)₂}(Phen=1,10-菲咯啉,Nap=1-萘甲酸,EtOH=乙醇)的合成、晶体结构及性质

Synthesis, Crystal Structure and Properties of Dinuclear Copper(Ⅱ) Complex {[Cu(Phen)(Nap)₂]₂·(EtOH)₂·(H₂O)₂} (Phen=1,10-Phenanthroline; Nap=1-Naphthoic Acid; EtOH=Ethyl Alcohol)

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