水相或无溶剂绿色催化合成双吲哚基甲烷研究进展

doi:10.19894/j.issn.1000-0518.200369

摘要/Abstract

摘要： 评价绿色催化合成方法的主要标准包括催化剂、试剂或溶剂、反应条件和后处理等。随着绿色化学的不断发展,水相催化或无溶剂合成表现出明显的优势,在催化双吲哚基甲烷衍生物的合成方面更是受到广泛的关注。但是目前尚无针对吲哚基甲烷催化反应过程以及是否使用试剂或溶剂等相关问题的综述报道。因此,对近十年来水相或无溶剂催化合成吲哚基甲烷的反应方法进行了综述,其目的是为指导和设计更为绿色、洁净的合成吲哚基甲烷新方法和思路,尤其在水相和无溶剂催化方面。

关键词: 双吲哚基甲烷衍生物, 水相催化, 无溶剂合成

Abstract: The main criteria for evaluating green catalytic synthesis methods include catalysts, reagents or solvents, reaction conditions, and post-treatment. With the continuous development of green chemistry, water-phase catalysis or solvent-free synthesis shows obvious advantages, and has attracted extensive attention in the synthesis of bis-indolyl methane derivatives. However, there is no review article report on the process of indolyl methane catalytic reaction and the related questions whether to use reagents or solvents. Therefore, this paper reviews the reactions for the synthesis of indolyl methane in the past decade. The purpose is to guide the development of greener and cleaner methods for the synthesis of indolymethane, especially under aqueous and solvent-free catalysis

Key words: Bis(indolyl)methanes, Aqueous catalysis, Solvent-free synthesis

中图分类号:

O621

吴之强, 韩新宁, 刘阳, 王刚, 詹海鹃, 刘万毅. 水相或无溶剂绿色催化合成双吲哚基甲烷研究进展[J]. 应用化学, 2021, 38(8): 881-896.

WU Zhi-Qiang, HAN Xin-Ning, LIU Yang, WANG Gang, ZHAN Hai-Juan, LIU Wan-Yi. Research Progress on Synthesis of Bis(indolyl)methanes under Aqueous or Solvent-free Catalysis[J]. Chinese Journal of Applied Chemistry, 2021, 38(8): 881-896.

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