Synthesis of Polyethylene Glycol Aldehyde Derivatives by Ozonation

doi:10.11944/j.issn.1000-0518.2019.01.180212

Chinese Journal of Applied Chemistry ›› 2019, Vol. 36 ›› Issue (1): 120-122.DOI: 10.11944/j.issn.1000-0518.2019.01.180212

• Communications • Previous Articles

Synthesis of Polyethylene Glycol Aldehyde Derivatives by Ozonation

LÜ Wenqiang^a^b,GENG Chao^a^*(),XU Jingwei^a^*()

^aState Key Laboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China
^bUniversity of Chinese Academy of Sciences,Beijing 100049,China

Received:2018-06-13 Accepted:2018-09-12 Published:2019-01-01 Online:2019-01-04
Contact: GENG Chao,XU Jingwei
Supported by:
Supported by the National Natural Science Foundation of China(No.61504145)

Abstract

Abstract:

Methoxypolyethylene glycol olefin was obtained by olefination of methoxypolyethylene glycol, and followed by ozonation to give methoxypolyethylene glycol aldehyde derivative. The properties of products were characterized by nuclear magnetic resonance spectroscopy(NMR) and matrix-assisted laser desorption/ionization time of flight mass spectrometry(MALDI-TOF-MS). The results show that the product has high purity and no by-products. The yields of methoxy polyethylene glycol acetaldehyde and polyethylene glycol propionaldehyde are as high as 98% and 99%, respectively, and the degrees of substitution are 90.87%~99.91% and 98%~100%, respectively.

Key words: polyethylene glycol, ozonation, aldehyde

LÜ Wenqiang,GENG Chao,XU Jingwei. Synthesis of Polyethylene Glycol Aldehyde Derivatives by Ozonation[J]. Chinese Journal of Applied Chemistry, 2019, 36(1): 120-122.

[1]	Yao CHEN, Ying TANG. Determination of Hydrazine in Clozapine by Precolumn Derivatization High Performance Liquid Chromatography Method [J]. Chinese Journal of Applied Chemistry, 2022, 39(02): 322-331.
[2]	ZHANG Cheng-Lu, BAO Jin-Di, YU Feng-Ming, DONG Wen-Jing, ZHANG Yang, GONG Rong-Qing, ZHANG Yan-Peng, ZHANG Lu. Synthesis and Application of a Fluorescence Probe with Quinazolinone as the Core Block for Highly Selective and Sensitive Detection of Hypochlorite Ion [J]. Chinese Journal of Applied Chemistry, 2021, 38(8): 986-994.
[3]	TIAN Shu-Yang, LYU Rong-Wen. Solvent-Free Oxidation of Benzyl Alcohol to Benzaldehyde Catalyzed by Magnesium Oxide Supported Bimetallic Gold-Palladium [J]. Chinese Journal of Applied Chemistry, 2021, 38(7): 789-799.
[4]	HE Yufang, YAN Pinping, HUANG Baoquan, LUO Fubin, LI Hongzhou, QIAN Qingrong, CHEN Qinghua. Thermal Conductivity and Crystallization Behavior of Polyethylene Glycol/Boron Nitride Phase Change Composites [J]. Chinese Journal of Applied Chemistry, 2020, 37(6): 650-657.
[5]	Lihui ZENG,Yuefeng LI,Haoxiang YAN,Yongkang ZENG,Zhixiang ZHANG,Zhongwen LIU,Zhaotie LIU. Catalytic Hydrogenation Performance of p-tert-Butyl-α-Methyl Cinnamaldehydeover Precious Metal Catalysts [J]. Chinese Journal of Applied Chemistry, 2020, 37(3): 322-331.
[6]	QI Yanxin, HUANG Yubin, JIN Ningyi. Preparation and Release Behavior of Progesterone Nano Micelles in Vitro [J]. Chinese Journal of Applied Chemistry, 2020, 37(11): 1340-1342.
[7]	SAN Xiaoguang, GONG Xiaohui, LU Yiming, QIAO Tongtong, YOU Yu, MENG Dan. Synthesis of NiO-WO₃ Nanocubes and Their Application in Detecting Formaldehyde [J]. Chinese Journal of Applied Chemistry, 2020, 37(10): 1203-1210.
[8]	AN Pinping, LUO Fubin, HUANG Baoquan, XIAO Liren, QIAN Qingrong, LI Hongzhou, CHEN Qinghua. Properties of Thermal Conductivity Enhanced Polyethylene Glycol-Based Phase Change Composites [J]. Chinese Journal of Applied Chemistry, 2020, 37(1): 46-53.
[9]	GAO Man, HE Xin, CUI Jingnan, LIU Tao, TIAN Zhenhao, HE Shengui. A Coumarin-Based Fluorescent Probe for Rapid Detection of Endogenous Formaldehyde [J]. Chinese Journal of Applied Chemistry, 2019, 36(9): 1053-1060.
[10]	HEI Jiahui, YANG Lining, LI Jun. Synthesis and Photocatalysis of Metal Complexes with Schiff Base Derived from 2-Thiophene Carboxaldehyde and Ethylenediamine [J]. Chinese Journal of Applied Chemistry, 2019, 36(8): 949-957.
[11]	JIN Zhenkang, LIU Hewen. Synthesis of Cyclophanealdehyde by Ultraviolet Irradiation [J]. Chinese Journal of Applied Chemistry, 2019, 36(12): 1371-1375.
[12]	JIN Zhenkang, LIU Hewen. Synthesis of Cyclophanealdehyde by Ultraviolet Irradiation [J]. Chinese Journal of Applied Chemistry, 2019, 36(12): 0-0.
[13]	Chunlin YANG, Yonglan FENG, Fuxing ZHANG, Jiangxi YU, Wujiu JIANG, Daizhi KUANG. Syntheses, Struture and Herbicidal Activity of Bis(substituted salicylaldehyde) Carbohydrazide n-Butyltin Complexes [J]. Chinese Journal of Applied Chemistry, 2018, 35(7): 795-801.
[14]	LI Fei,MAO Shengxue,SUN Yue,LÜ Chengwei,AN Yue. Dipotassium Hydrogenphosphate Assisted Multi-component One-Pot Synthesis of 1,4-Hihydropyrano[2,3-c]pyrazole Derivatives [J]. Chinese Journal of Applied Chemistry, 2018, 35(10): 1201-1207.
[15]	SHI Yun, LI Mengsheng, WEI Xiaolin. Synthesis of N,N-Isoquinoline Dipoles via Intramolecular Cyclization of o-Alkynylbenzaldehyde Hydrazones [J]. Chinese Journal of Applied Chemistry, 2017, 34(7): 795-800.

Synthesis of Polyethylene Glycol Aldehyde Derivatives by Ozonation

RichHTML

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments