Recent Advances in Radical Trifluoromethylation Reactions

doi:10.3724/SP.J.1095.2014.30378

Chinese Journal of Applied Chemistry

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Recent Advances in Radical Trifluoromethylation Reactions

ZENG Wei, CHEN Fuxue^*

(School of Chemical Engineering & the Environment,Beijing Institute of Technology,Beijing 100081,China)

Received:2013-07-25 Revised:2013-09-26 Published:2014-06-10 Online:2014-06-10
Contact: fuxue chen

Abstract

Abstract: In recent years, research on trifluoromethylation reactions have been developed rapidly. Since the special chemical and physical properties of the trifluoromethyl group, it plays an increasingly important role in the fields of medicine, pesticides and materials. As the result, a new recognition of radical trifluoromethylation has been achieved along with the development of organofluorine chemistry. This article delivered an overview of the recent progress of radical trifluoromethylation from the perspective of various radical trifluoromethylative precursors as well as reaction mechanisms.

Key words: free radical reactions, trifluoromethylation, photoredox catalysis, trifluoromethyl reagent, single electron , transfer

CLC Number:

O621.3

ZENG Wei, CHEN Fuxue*. Recent Advances in Radical Trifluoromethylation Reactions[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2014.30378.

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Recent Advances in Radical Trifluoromethylation Reactions

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