Chinese Journal of Applied Chemistry ›› 2019, Vol. 36 ›› Issue (2): 123-136.DOI: 10.11944/j.issn.1000-0518.2019.02.180116

• Review • Previous Articles     Next Articles

Research Progress on Bioimaging with the Second Near-infrared Fluorescence Probes

SU Zhea,QIN Wenjinga,BAI Leia,SUN Pengfeib,YU Changmina*(),FAN Qulib,LI Lina*()   

  1. aKey Laboratory of Flexible Electronics(KLOFE) & Institute of Advanced Materials(IAM),Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM),Nanjing Tech University(NanjingTech),Nanjing 211816,China;
    bKey Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors,Institute of Advanced Materials(IAM),Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM),Nanjing University of Posts & Telecommunications,Nanjing 210023,China;
  • Received:2018-04-16 Published:2019-02-01 Online:2019-01-31
  • Contact: YU Changmin,LI Lin
  • Supported by:
    Supported by the National Natural Science Foundation of China(No.81672508, No.61505076, No.21708034), the Jiangsu Provincial Foundation for Distinguished Young Scholars(No.BK20170041)

Abstract:

Due to simple operation, high resolution and real-time imaging,fluorescence technology has been widely used in detection and bioimaging. The second near-infrared window dyes(NIR-Ⅱ, 10001700 nm) have longer emission wavelength, less interference with light scattering and tissue autofluorescence, resulting in higher temporal and spatial resolution and deeper imaging depth in tissue imaging. In this review, we mainly introduce the designed mechanism and research progress in bioimaging based on NIR-Ⅱ dyes, and further give an outlook in the following studies.

Key words: second near-infrared, fluorescenceimaging, nanomaterials, conjugated polymer