Preparation and Antioxidant Activity of Novel Double Quaternary Ammonium Salt Derivative of Chitosan

doi:10.11944/j.issn.1000-0518.2015.03.140209

Chinese Journal of Applied Chemistry ›› 2015, Vol. 32 ›› Issue (3): 322-326.DOI: 10.11944/j.issn.1000-0518.2015.03.140209

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Preparation and Antioxidant Activity of Novel Double Quaternary Ammonium Salt Derivative of Chitosan

YANG Longqiang, LI Rongchun^*, LIANG Shaoping

College of Chemistry and Chemical Engineering,Dezhou University,Dezhou,Shandong 253023,China

Received:2014-06-12 Accepted:2014-10-30 Published:2015-03-02 Online:2015-03-02
Contact: Rongchun LI
Supported by:
Supported by National Natural Science Foundation of China(No.21371028);Colleges and Universities in Shandong Province Science and Technology Plan Projects(No.J13LD55);National Undergraduate Training Programs for Innovation and Entrepreneurship(No.201310448028)

Abstract

Abstract:

Water soluble chitosan quaternary ammonium salt derivative (HTCC) was prepared via reaction of chitosan and 2,3-epoxy propyl trimethyl ammonium chloride (CAT) firstly. Secondly, CAHTCC was obtained by reaction of chloroacetyl chloride and HTCC. Finally, double quaternary ammonium salt derivative of chitosan (PAHTCC) was synthesized by reaction of pyridine and CAHTCC. The structure of HTCC, CAHTCC and PAHTCC were characterized by FT-IR and ¹³C NMR. The HO·, ·O^2-, ·DPPH scavenging activities of the derivatives were tested. The results show that, the antioxidant activity of PAHTCC is enhanced comparing with chitosan, HTCC and CAHTCC. The HO·, ·O^2-, ·DPPH scavenging rate of PAHTCC is 68.5%, 74.3% and 80.8% at 1.6 g/L, respectively. The reason may be attributed to the double quaternary ammonium salt structure in PAHTCC molecule.

Key words: chitosan, double quaternary ammonium salt, antioxidant

CLC Number:

YANG Longqiang, LI Rongchun, LIANG Shaoping. Preparation and Antioxidant Activity of Novel Double Quaternary Ammonium Salt Derivative of Chitosan[J]. Chinese Journal of Applied Chemistry, 2015, 32(3): 322-326.

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Preparation and Antioxidant Activity of Novel Double Quaternary Ammonium Salt Derivative of Chitosan

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