Chinese Journal of Applied Chemistry

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Determination of Epinephrine by Graphene/Platinum Nanoparticle Hybrid Membrane Modified Electrode

GUO Xianhou1,2, WNAG Xueliang1, YU Zhangyu1,3*   

  1. (1.Department of Chemistry and Chemical Engineering,Heze University,Heze 274015,China;
    2.Hongda Chemical Engineering Co.,Ltd.,Zhaozhuang Mining Group,Tengzhou,277500,China;
    3.Jining University,Qvfu 273165,China)
  • Received:2013-12-03 Revised:2014-03-24 Published:2014-11-08 Online:2014-11-08

Abstract: Graphene/platinum nanoparticles hybrid membrane modified electrode was prepared by cyclic voltammetry(CV). The electrochemical behaviors of epinephrine(EP) were studied on this modified electrode, and an electrochemical method for determination of EP was developed. The morphology and the electrochemical properties of the modified electrode were characterized by scan electron microscopy(SEM) and cyclic voltammetry, respectively. The conditions that influenced the electrochemical properties of the modified electrode during the preparation processes and the conditions for determination of EP were optimized. Experimental results show that the modified electrode has excellent catalytic properties for the redox of EP. In the Na2HPO4citric acid buffer solution(pH=5.0), the oxidative peak current of EP is linear with its concentration in the range of 4.4×10-8~2.2×10-6 mol/L. The linear regressive equation is ipa(10 μA)=0.0753c(mol/L)+3.7653×10-5 with r=0.9989, and the detection limit of 2.0×10-9 mol/L(S/N=3). The modified electrode shows good reproducibility, high sensitivity and selectivity. It could be used for determination of the content of EP in real samples.

Key words: graphene, platinum nanoparticle, hybrid material, epinephrine

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