一种罗丹明衍生物的合成及其对三价金属离子(Fe3+、Cr3+和Al3+)的识别

doi:10.11944/j.issn.1000-0518.2017.05.160475

摘要/Abstract

摘要：

三价金属离子(Cr³⁺、Fe³⁺和Al³⁺)与人体健康密切相关。目前,检测Cr³⁺、Fe³⁺和Al³⁺需要采用不同的荧光探针,增加了检测成本和检测时间。发展能够同时检测Cr³⁺、Fe³⁺和Al³⁺的高灵敏度和强抗干扰能力的荧光探针具有非常重要的意义。本文以罗丹明B为原料,合成和表征了一种罗丹明类荧光增强型探针(P),并研究了其光谱性质。研究表明,在V(甲醇)：V(水)=9：1体系中对三价金属离子Fe³⁺、Cr³⁺和Al³⁺具有较高的选择性,不受其它二价金属离子及一价金属离子的影响,抗干扰能力强。同时,探针P对三价金属离子具有较高的灵敏度,对Cr³⁺、Al³⁺和Fe³⁺的检测限分别为3.0×10^-4、2.7×10^-4和1.0×10^-4 mol/L,表明其可用于Cr³⁺、Al³⁺和Fe³⁺的检测。

关键词: 罗丹明, 探针, 三价金属离子

Abstract:

Trivalent metallic ions(Cr³⁺, Fe³⁺ and Al³⁺) play important roles in environment and human health. It is exhausting using different sensor in different conditions for detection of all the trivalent metallic ions. Single probes for detecting all of these trivalent metallic cations simultaneously with high sensitivity and selectivity have attracted great attention. A novel rhodamine-based probe P was synthesized from rhodamine B. It is showed that probe P acts as a “turn on” fluorescent probe for trivalent metallic ions(Fe³⁺, Cr³⁺ and Al³⁺) recognition. Probe P is highly selective to trivalent metallic ions over other monovalent or divalent metallic ions in V(CH₃OH)：V(Tris-HCl)=9：1. Furthermore, probe P is highly sensitive to trivalent metallic ions. The detection limits of probe P for Cr³⁺, Al³⁺ and Fe³⁺ are 3.0×10^-4, 2.7×10^-4 and 1.0×10^-4 mol/L, respectively. Probe P could be used in the detection of Cr³⁺, Al³⁺ and Fe³⁺.

Key words: rhodamine, probe, trivalent ions

侯淑华, 刘冬, 曲忠国, 钟克利, 边延江, 汤立军. 一种罗丹明衍生物的合成及其对三价金属离子(Fe³⁺、Cr³⁺和Al³⁺)的识别[J]. 应用化学, 2017, 34(5): 606-610.

HOU Shuhua, QU Zhongguo, ZHONG Keli, BIAN Yanjiang, TANG Lijun. Synthesis of a Novel Rhodamine-Based Probe and Its Selective Detection of Trivalent Metallic Ions[J]. Chinese Journal of Applied Chemistry, 2017, 34(5): 606-610.

参考文献

[1]	Perl D P,GajdusekD C,GarrutoR M,et al. Intraneuronal Aluminum Accumulationin Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia of Guam[J]. Science,1982,217(4564):1053-1055.
[2]	Crapper D,Krishnan S,Dalton A. Brain Aluminum Distribution in Alzheimer's Diseaseand Experimental Neurofibrillary Degeneration[J]. Science,1973,180(4085):511-513.
[3]	Pithadia A S,Lim M H. Metal-associated Amyloid-β Species in Alzheimer's Disease[J]. Curr Opin Chem Biol,2012,16(1):67-73.
[4]	Weizman H,Ardon O,Mester B,et al. Fluorescently-labeled Ferrichrome Analogsas Probes for Receptor-mediated, Microbial Iron Uptake[J]. J Am Chem Soc,1996,118(49):12368-12375.
[5]	Touati,D.Iron and Oxidative Stress in Bacteria[J]. Arch Biochem Biophy,2000,373(1):1-6.
[6]	Singh A K,Gupat V,Gupta B. Chromium(Ⅲ) Selective Membrane Sensors Basedon Schiff Bases as Chelating Ionophores[J]. Anal Chim Acta,2007,585(1):171-178.
[7]	Vincent J B. Quest for the Molecular Mechanism of Chromium Action and Its Relationship to Diabetes[J]. Nutr Rev,2000,58(3):67-72.
[8]	Lv Y,Zhu L,Liu H,et al. Single-fluorophore-based Fluorescent Probes Enable Dual-channel Detection of Ag+ and Hg2+ with High Selectivity and Sensitivity[J]. Anal Chim Acta,2014,839(1):74-82.
[9]	Zhan S,Xu H,Zhang D,et al. Fluorescent Detection of Hg2+ and Pb2+ Using Gene Finder(TM) and an Integrated Functional Nucleic Acid[J]. Biosens Bioelectron,2015,72(68):95-99.
[10]	Maiti S,Aydin Z,Zhang Y,et al. Reaction-based Turn-On Fluorescent Probes with Magnetic Responses for Fe2+ Detectionin Live Cells[J]. Dalton Trans,2015,44(19):8942-8949.
[11]	Prabhu J,Velmurugan K,Nandhakumar R. Pb2+ Ion Induced Self-assembly of Anthracene Based Chalcone with a Fluorescence Turn on Processin Aqueous Media[J]. J Anal Chem,2015,70(8):943-948.
[12]	Antony E J,Raj M,Paulpandi R Q,et al. A Highly Selective Fluorescent Sensor for Pb2+ Based on a Modified Beta-cyclodextrin[J]. J Fluoresc,2015,25(4):1031-1036.
[13]	Geng T M,Wu D Y,Huang W,et al. Fluorogenic Detection of Hg2+, Cd2+, Fe2+, Pb2+ Cationsin Aqueous Media by Means of an Acrylamide-acrylic Acid Copolymer Chemosensor with Pendant Rhodamine-based Dyes[J]. J Polym Res,2014,21(3):354-361.
[14]	Azadbakht R,Vaisi H,Mohamadvand H,et al. A New Fluorescent Chemosensor for Pb2+ Ions Based on Naphthalene Derivatives[J]. Spectrochim Acta A,2015,145:575-579.
[15]	Mao J,Wang L N,Dou W,et al. Tuning the Selectivity of Two Chemosensors to Fe3+ and Cr3+[J]. Org Lett,2007,9(22):4567-4570.
[16]	Chereddy N R,Nagaraju P,Raju M V,et al. A Novel FRET ‘Off-On’ Fluorescent Probe for the Selective Detection of Fe3+, Al3+ and Cr3+ Ions:Its Ultrafast Energy Transfer Kinetics and Applicationin Live Cell Imaging[J]. Biosens Bioelectron,2015,68:749-756.
[17]	Hou S H,Qu Z G,Zhong K L,et al. A New Rhodamine-based Visual and Fluorometric Probe for Selective Detection of Trivalent Cations[J]. Tetrahedron Lett,2016,57(24):2616-2619.
[18]	HOU Shuhua,QU Zhongguo,ZHONG Keli,et al. Synthesis of a Novel Benzothiazole-Rhodamine Derivative and Its Selective Detection of Fe3+, Al3+ and Cr3+[J]. Chinese J Org Chem,2016,36(4):768-773(in Chinese). 侯淑华,曲忠国,钟克利,等. 一种苯并噻唑-罗丹明衍生物的合成及其对Fe3+、Al3+、Cr3+的识别[J]. 有机化学,2016,36(4):768-773.

一种罗丹明衍生物的合成及其对三价金属离子(Fe³⁺、Cr³⁺和Al³⁺)的识别

Synthesis of a Novel Rhodamine-Based Probe and Its Selective Detection of Trivalent Metallic Ions

RichHTML

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	于红丽, 周思仪, 洪琛, 罗稳. 基于黄酮骨架的“关-开”型荧光探针用于检测活细胞内丁酰胆碱酯酶[J]. 应用化学, 2023, 40(4): 500-508.
[2]	耿佳美, 马素芳, 刘文, 刁海鹏, 武志芳, 李思进. 肝靶向荧光探针用于HepG2细胞中ONOO^-的特异性检测[J]. 应用化学, 2023, 40(3): 441-448.
[3]	杨倩, 张杨, 赖明阳, 郭琳, 郏建波. 不同热解温度下制备的磁性生物炭对罗丹明B的吸附性能[J]. 应用化学, 2023, 40(2): 288-298.
[4]	卫小燕, 张金艳, 盛兰, 张晓安. Off-on/On-off双模式水致变色材料：水诱导微环境酸度改变调控罗丹明衍生物颜色切换[J]. 应用化学, 2022, 39(7): 1119-1128.
[5]	薛松松, 解正峰, 何佳伟, 张天怡, 夏保平, 李雨芹. 高选择性快速识别汞（Ⅱ）离子的磺酰腙型探针的合成及在吸附中的应用[J]. 应用化学, 2022, 39(5): 760-768.
[6]	黄蕊, 叶长青, 李亚军, 邱盟峯, 李达谅, 鲍红丽. 线粒体靶向的近红外HClO/ClO^－荧光探针的研究进展[J]. 应用化学, 2022, 39(3): 407-424.
[7]	张成路, 王一鸣, 任芷漩, 李露, 李雨晴, 宋府璐. 以苯并咪唑萘酰亚胺为荧光团高选择快速检测H₂S的荧光探针[J]. 应用化学, 2022, 39(3): 489-497.
[8]	于思为, 王良鹏, 金日哲, 康传清. 氧杂蒽类荧光探针对ClO^－的识别和细胞成像应用[J]. 应用化学, 2022, 39(12): 1903-1911.
[9]	闫美玲, 彭红珍, 左婷婷, 田甜, 诸颖, 孙艳红. 四面体框架核酸对脑靶向肽分子的可控组装及性能[J]. 应用化学, 2022, 39(10): 1501-1509.
[10]	侯淑华, 李仕琦, 汤立军. 新型水溶性罗丹明类荧光探针的合成及其对游离3价金属离子的识别[J]. 应用化学, 2022, 39(02): 241-246.
[11]	张成路, 暴金迪, 于丰铭, 董文静, 张洋, 宫荣庆, 张彦朋, 张璐. 以喹唑啉酮为核心高选择高灵敏识别次氯酸根离子的荧光探针的合成及应用[J]. 应用化学, 2021, 38(8): 986-994.
[12]	黄译文, 王丽艳, 赵冰, 宋波. 一种水溶性甲氧基萘乙烯半菁合成及对铬(Ⅲ)离子的荧光检测[J]. 应用化学, 2021, 38(11): 1503-1511.
[13]	胡国文, 乔玉玲. 叶酸修饰的碳量子点在体外癌细胞成像中的应用[J]. 应用化学, 2020, 37(9): 1003-1009.
[14]	胡国文, 乔玉玲. 叶酸修饰的碳量子点在体外癌细胞成像中的应用[J]. 应用化学, 2020, 37(9): 0-0.
[15]	徐丽萍, 刘清士, 董芷辰, 郭兴家, 董微. 基于氮掺杂碳点的荧光增强简便、快速而准确地检测环丙沙星[J]. 应用化学, 2020, 37(7): 830-838.