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新型含紫罗兰酮基查尔酮的合成与表征

刘长辉,文瑞明*,叶晓琴,易先文,方磊   

  1. (湖南城市学院化学与环境工程系 益阳 413000)
  • 收稿日期:2011-07-28 修回日期:2011-09-01 出版日期:2012-07-10 发布日期:2012-07-10
  • 通讯作者: 文瑞明，教授; Tel/Fax:0737-6353218; E-mail:wenruiming@sohu.com; 研究方向：有机合成
  • 基金资助:
    国家自然科学基金资助项目（51074069）；湖南省科技计划项目（2010GK3161）；益阳市科技计划项目（2011JZ36）

Synthesis and Characterization of Ionone-containing Chalcones

LIU Changhui, WEN Ruiming*, YE Xiaoqin, YI Xianwen, FANG Lei   

  1. (Department of Chemistry and Environmental Engineering,Hunan City University,Yiyang 413000,China)
  • Received:2011-07-28 Revised:2011-09-01 Published:2012-07-10 Online:2012-07-10

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被引次数

1 | 1

摘要： 在碳酸钠和氢氧化钠催化下，β-紫罗兰酮和5,6-环氧-β-紫罗兰酮与芳香醛于室温下研磨1～15 min，制备了8种新型含紫罗兰酮基查尔酮，其结构经1H NMR、MS、IR和元素分析表征。 结果表明，β-紫罗兰酮、苯甲醛、Na2CO3与NaOH的物质的量比为20∶20∶5∶15时，收率可达87.1%～94.8%，苯甲醛环上吸电子基团可促进反应进行。

关键词: 查尔酮, &, beta, -紫罗兰酮, 环氧-&, beta, -紫罗兰酮, 缩合反应, 合成

Abstract: Condensation of β-ionone and 5,6-epoxyl-β-ionone with aromatic aldehydes by sodium carbonate and sodium hydroxide was carried out to afford eight novel ionone-containing chalcones at room temperature for 1～15 min by grinding, and their structures were characterized by 1H NMR, MS, IR and elemental analysis. The effects of substituents, the types and amounts of catalysts on the reaction were studied. The results show that the yield is 87.1%～94.8% when the molar ratio of β-ionone, benzalaldehyde, sodium carbonate and sodium hydroxide is 20∶20∶5∶15, and electron withdrawing group promotes the condensation.

Key words: chalcone, &, beta, -ionone, epoxy-&, beta, -ionone, condensation, synthesis

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