Synthesis and Application of a New Water-Soluble Salicylic Acid Based Sensor for Recognition of Fe（Ⅲ）

doi:10.19894/j.issn.1000-0518.240235

Chinese Journal of Applied Chemistry ›› 2025, Vol. 42 ›› Issue (6): 802-810.DOI: 10.19894/j.issn.1000-0518.240235

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Synthesis and Application of a New Water-Soluble Salicylic Acid Based Sensor for Recognition of Fe（Ⅲ）

Mei-Hua BIAN¹^,²(), Yu-Yin HE¹, Jia-Ning PENG¹^,², Xing-Sen ZHANG¹, Song-Lin QIN¹

^1.Electric Power Research Institute of Guangxi Power Grid Co. ，Ltd. ，Nanning 530023，China
^2.Guangxi Key Laboratory of Intelligent Control and Maintenance of Power Equipment，Nanning 530023，China

Received:2024-07-29 Accepted:2025-05-06 Published:2025-06-01 Online:2025-07-01
Contact: Mei-Hua BIAN
About author:27250060@qq.com
Supported by:
Guangxi Power Grid Corporation Science and Technology Project(GXKJXM20230096)

Abstract

Abstract:

A new salicylic acid derivative （Z）-5-（（1，3-dihydroxy-2-（hydroxymethyl） propan-2-ylimino） methyl-2-hydroxybenzoic acid （Tris-SA） was synthesized through the condensation reaction of 5-formylsalicylic acid with tris（hydroxymethyl）-aminomethane and was utilized for the colorimetric recognition of Fe³⁺ in complex systems. Tris-SA exhibits good water solubility and no absorption in the visible light region. Upon the addition of Fe³⁺， a new absorption peak appears at 500 nm and the solution color changes from colorless to purple-red. Based on the linear relationship between the intensity of the absorption spectrum at 500 nm and the concentration of Fe³⁺， the detection limit was determined to be 3.421×10^-6 mol/L. The influence of different pH values and the presence of metal ions on the Fe³⁺ recognition capability of Tris-SA was also studied， and the performance of Tris-SA in recognizing Fe³⁺ was compared with that of commercial indicators salicylic acid and sulfosalicylic acid.

Key words: Salicylic acid derivative, Absorption, Fe³⁺ ion, Colorimetric recognition

CLC Number:

O625.5

Mei-Hua BIAN, Yu-Yin HE, Jia-Ning PENG, Xing-Sen ZHANG, Song-Lin QIN. Synthesis and Application of a New Water-Soluble Salicylic Acid Based Sensor for Recognition of Fe（Ⅲ）[J]. Chinese Journal of Applied Chemistry, 2025, 42(6): 802-810.

Figures/Tables 8

Fig.1 Synthetic route of the probe Tris-SA

Fig.2 （A） 1H NMR and （B） 13C NMR spectra of the probe Tris-SA in DMSO solution

Fig.3 （A） Normalized UV-Vis spectra of probe Tris-SA （1×10-4 mol/L） in different solvents；（B） UV-Vis spectra of Tris-SA （1×10-4 mol/L） in pH （3， 6.8， 12） values

Fig.4 （A） UV-Vis spectra of Tris-SA （1×10-4 mol/ L） after addition of 5×10-4 mol/L different metal ions in aqueous solution；（B） Absorption histogram at 500 nm of Tris-SA （1×10-4 mol/L） after addition of 5×10-4 mol/L different metal ions， Insert ： The color change before and after adding 5×10-4 mol/L Fe3+ in aqueous solution containing Tris-SA （1×10-4 mol/L）；（C） UV-Vis spectra of Tris-SA to Fe3+ at 500 nm under different pH 2～12；（D） UV-Vis spectra of Tris-SA （1×10-4 mol/L） at 500 nm first adding 5×10-4 mol/L different metal ions and then 5×10-4 mol/L Fe3+ （the red bar graph indicates the absorbance of the system with the addition of other metal ions， and the green color indicates the absorbance after the addition of other metal ions followed by the addition of 5×10-4 mol/L Fe3+）；（E） UV-Vis spectra of Tris-SA/Fe3+ （1×10-4 mol/L/5×10-4 mol/L） with addition different amount of Zn2+；（F） UV-Vis spectra of Tris-SA/Fe3+ （1×10-4 mol/L/5×10-4 mol/L） with addition different amount of Fe2+

Fig.5 （A） UV-Vis spectra Tris-SA （1×10-4 mol/L） after adding different amount of Fe3+ （0~4.5×10-4 mol/L）；（B） The relationship between the absorbance of Tris-SA at 500 nm and the concentration of Fe3+；（C） Linear curve of absorbance of Tris-SA at 500 nm （0~3×10-4 mol/L Fe3+）

Fig. 6 （A） Job's curve diagram of Tris-SA and Fe3+；（B） FT-IR spectra of Tris-SA before and after adding Fe3+；（C） The proposed binding mechanism between Tris-SA and Fe3+

Table 1 Solubility of Tris-SA and commercial iron indicators in different acid and alkali environments

	pH=4	pH=6.8	pH=10
ρ（SA）/（g·L^-1）	1.67	1.80	1.92
ρ（SSA）/（g·L^-1）	100.0	180	270
ρ（Tris-SA）/（g·L^-1）	108.92	115.7	87.4

Fig.7 （A） UV-Vis spectra of SA （1×10-4 mol/L）， SSA （1×10-4 mol/L）， and Tris-SA （1×10-4 mol/L） before and after adding 3 equivalents of Fe3+ in Tris-HCl buffer solution （pH=6.8）；（B） Linear relationship diagram between the absorption at 500 nm of SA （1×10-4 mol/L）， SSA （1×10-4 mol/L）， Tris-SA （1×10-4 mol/L） and the concentration of Fe3+

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Synthesis and Application of a New Water-Soluble Salicylic Acid Based Sensor for Recognition of Fe（Ⅲ）

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