Synthesis, Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives

doi:10.3724/SP.J.1095.2014.30454

Chinese Journal of Applied Chemistry

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Synthesis, Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives

SONG Bin¹, ZHENG Changzheng^1*, ZHANG Mingkai², XU Shouwei¹, REN Lidi¹

(1.School of Environmental and Chemical Engineering,Xi′an Polytechnic University,Xi′an 710048,China;
2.School of Chemical Engineering and Biological Engineering,Zhejiang University,Hangzhou 310058,China)

Received:2013-09-09 Revised:2013-11-01 Published:2014-07-10 Online:2014-07-10
About author:Professor Zheng Channgzheng;Tel:029-82335828;E-mail：zhchangzheng@126.com;Research interests:Coal chemical technology and metal complex
which has biological activity

Abstract

Abstract: Four furan acylhydrazones derivatives(4a~4d) were synthesized from 2-furancarbaldehyde and benzohydrazide derivatives and characterized by using elemental analysis, 1H NMR, FT-IR,UV and fluorescence spectroscopy methods. The results show that the 2D chain layered structure was assembled through intermolecular hydrogen bonds and face to face π…π stacking interactions of the furan rings. The single crystal of acylhydrazone 4a was obtained through the solvent evaporation method. Its crystal and molecular structures were determined through X-ray scattering. Fluorescence test shows that the acylhydrazone 4c has strong fluorescence. All furan acylhydrazones were screened for their antibacterial activities to Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa by agar diffusion method. The result shows that acylhydrazone 4c has very significant antibacterial activity to Staphylococcus aureus. CCDC:947253

Key words: furan acylhydrazone, crystal structure, luminescence property, antibacterial activity

CLC Number:

O626

SONG Bin1, ZHENG Changzheng1*, ZHANG Mingkai2, XU Shouwei1, REN Lidi1. Synthesis, Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2014.30454.

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Synthesis, Luminescence Property and Antibacterial Activities of 2-Furoylhydrazone Derivatives

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