Chinese Journal of Applied Chemistry ›› 2009, Vol. 26 ›› Issue (12): 1395-1398.

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Preparation and evaluation of chiral stationary phase through grafting to polysiloxane

SUN Xi-Jun, YAO Jin-Shui*, ZHAO Yan   

  1. (College of Material Science and Engineering,Shandong Institute of Light Industry,Ji′nan 250353)
  • Received:2008-11-24 Revised:2009-03-20 Published:2009-12-10 Online:2009-12-10

Abstract:

With methyl-S-(-)-lactate, S-(-)-α-the phenethyl alcohol, (S)-(+)-2-butanol as chiral pool to synthesize new chiral unsaturated esters, under the catalytic of N,N'-dicyclohexyl carbodimide(DCC) and 4-dimethylaminopyridines. The production is characterized through the infrared spectrum analysis、NMR and organic ultimate analysis and purity product is obtained. Then we get chiral stationary phase through grafting to polysiloxane.

Key words: asymmetric synthesis,ester chiral monomer,chiral stationary phase,polysiloxane

CLC Number: