Chinese Journal of Applied Chemistry ›› 1993, Vol. 0 ›› Issue (2): 104-106.

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A FACILE SYNTHETIC METHOD OF 8-SUBSTITUTED GERANIOL

Zhang Hesheng, Chen Jiawei, Jiang Jilong   

  1. Department of Chemistry, Hubei University, 430062 Wuhan
  • Received:1992-04-29 Revised:1992-09-18 Published:1993-04-10 Online:1993-04-10

Abstract: 10, 11-Dihydrofarnesol (3a) and 6,7-dehydrophytol (3b), which are important in perfume and synthesis of vitamin E and K1, were prepared by reacting 6-chloro-3, 7-dimethyl-2, 7-octadi-enylpyrane (1) with isoamylmagnesium bromide and 3,7-dimethyloctylmagnesium bromide, respectively.

Key words: ene chlorination, substituted geraniol, Grignard reagent, coupling reaction, synthesis