Chinese Journal of Applied Chemistry

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Screening the Best Functional Monomer for Preparation of Molecularly Imprinted Polymer of 4-Nitrophenol and Its Application on Solid Phase Extraction of Water Sample

MUHAMMAD Kipayem, MUHAMMAD Turghun*, TURAHUN Yunusjan, YAKUP Burabiye   

  1. (College of Chemistry & Chemical Engineering,Xinjiang University,Key Laboratory of
    Oil and Gas Fine Chemicals,Educational Ministry of China,Urumqi 830046,China)
  • Received:2013-07-02 Revised:2013-09-17 Online:2014-04-10 Published:2014-04-10

Abstract: A new method for rational design of molecularly imprinted polymer(MIP) of 4-nitrophenol(4-NP) was established. Using the method, nonimprinted polymer(NIP) library screening, vinylimidazole was selected as the best functional monomer. Acetonitrile and trimethylolpropane trimethacrylate(TRIM) were the best polymerization solvent and crosslinker, respectively. Through the optimization of the solid phase extraction(SPE) profile, the best imprinting effect was achieved in pH=2.5 phosphate buffer, washing with the buffer containing 45% acetonitrile and eluting with methanol. The maximum adsorption capacity of the polymer was 5.8 mg/g. Extraction recoveries of imprinted polymers for 4-NP and its analogs, phenol and 4-chlorophenol, were found to be 96.0%, 78.8% and 77.8%, respectively, proving its high selectivity. It was also successfully used for SPE of 4-NP from spiked tap water with a recovery of 93.1%. The method is proved to be effective and fast for the preparation of MIPs.

Key words: molecularly imprinted polymer, solid phase extraction, nitrophenol, monomer screening, dummy-template

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