Chinese Journal of Applied Chemistry ›› 2010, Vol. 27 ›› Issue (02): 178-182.DOI: 10.3724/SP.J.1095.2010.90098

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Interaction between Silicotungstic Heteropolyacid and Ofloxacin

GAO Yan-Sheng1, ZHOU Qiu-Hua2, ZHANG Hong-Mei2, WANG Yan-Qing1*   

  1. (1.Yancheng Technician Institute,Yancheng;
    2.School of Chemistry and Chemical Engineering,Yancheng Teachers University,Yancheng 224002)
  • Received:2009-02-16 Revised:2009-05-11 Published:2010-02-10 Online:2010-02-10

Abstract:

A complex composed of ofloxacin(OFLX) and silicotungstic heteropolyacid (SiW) was studied by fluorescence and IR spectroscopy. SiW can quench the fluorescence of OFLX by forming a new complex. The binding site number n, apparent binding constant KA and corresponding thermodynamic parameters were measured at different temperatures. This indicates that the electrostatic and hydrophobic interactions play a major role in stabilizing the complex. The IR spectrum confirmed the presence of Keggin type anion in the SiW-OFLX complex.

Key words: silicotungstic heteropolyacid, ofloxacin, fluorescence spectroscopy, interaction

CLC Number: