Research Progress on Hydrophilic Photoswitchable Fluorescent Diarylethenes

doi:10.11944/j.issn.1000-0518.2017.12.170304

Chinese Journal of Applied Chemistry ›› 2017, Vol. 34 ›› Issue (12): 1379-1402.DOI: 10.11944/j.issn.1000-0518.2017.12.170304

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Research Progress on Hydrophilic Photoswitchable Fluorescent Diarylethenes

LI Chong(),CHEN Ying,XIE Nuohua,LIU Junxia,FAN Cheng,ZHOU Qiyuan,ZHU Mingqiang()

Wuhan National Laboratory for Optoelectronics,School of Optical and Electronic Information,Huazhong University of Science and Technology,Wuhan 430074,China

Received:2017-08-29 Accepted:2017-09-30 Published:2017-12-04 Online:2017-12-04
Contact: LI Chong,ZHU Mingqiang
Supported by:
Supported by the National Natural Science Foundation of China(No.51673077, No.51603078, No.21474034), the National Basic Research Program of China(No.2013CB922104, No.2015CB755602), the Fundamental Research Funds for the Central Universities(HUST:2016YXMS029), Director Fund of WNLO

Abstract

Abstract:

Photoswitchable fluorescent dithienylethene is one kind of the most typical diarylethene structures. Hydrophilization of photoswitchable fluorescent dithienylethene has become one of the key factors to come true its practical applications as a fluorescence photoswitching probes. Owing to its excellent fatigue resistance and unique thermal bistability, it has been widely studied and applied. This paper reviews the development history of photoswitchable fluorescent thienylethenes, summarizes the mechanism of fluorescence photoswitching mechanisms, describes some important achievements on the foundational research about novel structures and improved properties of photoswitchable fluorescent thienylethene in recent years. We also focus on the systemic overview of the applications of photoswitchable fluorescent dithienylethylene in optical memory, non-destructive read-out, single-molecule fluorescence imaging, bio-imaging, all-optical transistors. In the end, the challenges encountered during the study of diarylethenes are analyzed. It is believable that photoswithcable fluorescent polymers based on dithienylethene is the research direction in the future. Moreover, the promising application of diarylethenes in super-resolution imaging is prospected.

Key words: diarylethene, photoswitchable fluorescent molecules, hydrophilic, sensors, super-resolution imaging, fluorescence photoswitching probes

LI Chong,CHEN Ying,XIE Nuohua,LIU Junxia,FAN Cheng,ZHOU Qiyuan,ZHU Mingqiang. Research Progress on Hydrophilic Photoswitchable Fluorescent Diarylethenes[J]. Chinese Journal of Applied Chemistry, 2017, 34(12): 1379-1402.

References

[1]	Irie M,Mohri M. Thermally Irreversible Photochromic Systems. Reversible Photocyclization of Diarylethene Derivatives[J]. J Org Chem,1988,53(4):803-808.
[2]	LI Chong. The Synthesis,Properties and Applications of Photoswitchable Fluorescent Diarylethene[D]. Wuhan:Huazhong University of Science & Technology,2016(in Chinese). 李冲. 二芳基乙烯类荧光分子开关的合成、性质及应用[D]. 武汉:华中科技大学,2015.
[3]	Wigglesworth T J,Sud D,Norsten T B,et al.Chiral Discrimination in Photochromic Helicenes[J]. J Am Chem Soc,2005,127(20):7272-7273.
[4]	Irie M. Photochromism of Diarylethene Single Molecules and Single Crystals[J]. Photochem Photobiol Sci,2010,9(12):1535-1542.
[5]	Toriumi A,Kawata S,Gu M. Reflection Confocal Microscope Readout System for Three-Dimensional Photochromic Optical Data Storage[J]. Opt Lett,1998,23(24):1924-1926.
[6]	Uchida K,Saito M,Murakami A,et al.Non-Destructive Readout of the Photochromic Reactions of Diarylethene Derivatives Using Infrared Light[J]. Adv Mater,2003,15(2):121-125.
[7]	Stellacci F,Bertarelli C,Toscano F,et al.Diarylethene-Based Photochromic Rewritable Optical Memories:On the Possibility of Reading in the Mid-infrared[J]. Chem Phys Lett,1999,302(5/6):563-570.
[8]	Matsuda K. Photochromic Diarylethene as an Information Processing Unit:Magnetic and Electric Switching[J]. Pure Appl Chem,2008,80(3):555-561.
[9]	Barone V,Cacelli I,Ferretti A,et al.Electron Transport Properties of Diarylethene Photoswitches by a Simplified NEGF-DFT Approach[J]. J Phys Chem B,2014,118(18):4976-4981.
[10]	Kawai T,Koshido T,Yoshino K. Optical and Dielectric Properties of Photochromic Dye in Amorphous State and Its Application[J]. Appl Phys Lett,1995,67(6):795-797.
[11]	Irie M,Ishida H,Tsujioka T. Rewritable Near-Field Optical Recording on Photochromic Perinaphthothioindigo Thin Films:Readout by Fluorescence[J]. Jpn J Appl Phys,1999,38(10R):6114.
[12]	Tong Z,Pu S,Xiao Q,et al.Synthesis and Photochromism of a Novel Water-Soluble Diarylethene with Glucosyltriazolyl Groups[J]. Tetrahedron Lett,2013,54(6):474-477.
[13]	Zhang J,Zou Q,Tian H. Photochromic Materials:More Than Meets the Eye[J]. Adv Mater,2013,25(3):378-399.
[14]	Fukaminato T. Single-Molecule Fluorescence Photoswitching:Design and Synthesis of Photoswitchable Fluorescent Molecules[J]. J Photochem Photobiol,C,2011,12(3):177-208.
[15]	LI Chong,LIU Junxia,XIE Nuohua,et al.Research Progress on Photoswitchable Fluorescent Dithienylethenes[J]. Polym Bull,2015,(9):142-162(in Chinese). 李冲,刘俊霞,谢诺华,等. 二噻吩基乙烯荧光分子开关的研究进展[J]. 高分子通报,2015,(9):142-162.
[16]	Zou Y,Yi T,Xiao S,et al.Amphiphilic Diarylethene as a Photoswitchable Probe for Imaging Living Cells[J]. J Am Chem Soc,2008,130(47):15750-15751.
[17]	Matsuda K,Shinkai Y,Yamaguchi T,et al.Very High Cyclization Quantum Yields of Diarylethene Having Two N-Methylpyridinium Ions[J]. Chem Lett,2003,32(12):1178-1179.
[18]	Hirose T,Irie M,Matsuda K. Temperature-Light Dual Control of Clouding Behavior of an Oligo(ethylene glycol)-Diarylethene Hybrid System[J]. Adv Mater,2008,20(11):2137-2141.
[19]	Saitoh M,Fukaminato T,Irie M. Photochromism of a Diarylethene Derivative in Aqueous Solution Capping with a Water-Soluble Nano-Cavitand[J]. J Photochem Photobiol A:Chem,2009,207(1):28-31.
[20]	Xiao S,Zou Y,Yu M,et al.A photochromic Fluorescent Switch in an Organogel System with Non-destructive Readout Ability[J]. Chem Commun,2007,(45):4758-4760.
[21]	Liu J X,Xin B,Li C,et al.PEGylated Perylenemonoimide-Dithienylethene for Super-Resolution Imaging of Liposomes[J]. ACS Appl Mater Interfaces,2017,9(12):10338-10343.
[22]	Li C,Yan H,Zhao L X,et al.A Trident Dithienylethene-Perylenemonoimide Dyad with Super Fluorescence Switching Speed and Ratio[J]. Nat Commun,2014,5:5709.
[23]	Cheng H,Ma P,Wang Y,et al.Photoswitchable and Water-Soluble Fluorescent Nano-Aggregates Based on a Diarylethene Dansyl Dyad and Liposome[J]. Chem-Asian J,2017,12(2):248-253.
[24]	Feng G,Ding D,Li K,et al.Reversible Photoswitching Conjugated Polymer Nanoparticles for Cell and ex Vivo Tumor Imaging[J]. Nanoscale,2014,6(8):4141-4147.
[25]	Balter M,Li S,Morimoto M,et al.Emission Color Tuning and White-Light Generation Based on Photochromic Control of Energy Transfer Reactions in Polymer Micelles[J]. Chem Sci,2016,7(9):5867-5871.
[26]	Min Y K,Ji G C,Ahn K H,et al.Superparamagnetic Iron Oxide Nanoparticles with Photoswitchable Fluorescence[J]. Chem Commun,2008,(38):4622-4624.
[27]	Wu T,Wilson D,Branda N R. Fluorescent Quenching of Lanthanide-Doped Upconverting Nanoparticles by Photoresponsive Polymer Shells[J]. Chem Mater,2014,26(14):4313-4320.
[28]	Díaz S A,Gillanders F,Susumu K,et al.Water-Soluble, Thermostable, Photomodulated Color-Switching Quantum Dots[J]. Chem-Eur J,2017,23(2):263-267.
[29]	Li C,Hu Z,Aldred M P,et al.Water-Soluble Polymeric Photoswitching Dyads Impart Super-Resolution Lysosome Highlighters[J]. Macromolecules,2014,47(24):8594-8601.
[30]	Liu J X,Xin B,Li C,et al.Photoswitchable Polyfluorophores Based on Perylenemonoimide-Dithienylethene Conjugates as Super-Resolution MitoTrackers[J]. J Mater Chem C,2017,5(36):9339-9344.
[31]	Wu T,Boyer J C,Barker M,et al.A “Plug-and-Play” Method to Prepare Water-Soluble Photoresponsive Encapsulated Upconverting Nanoparticles Containing Hydrophobic Molecular Switches[J]. Chem Mater,2013,25(12):2495-2502.
[32]	Massaad J,Coppel Y,Sliwa M,et al.Photocontrol of Luminescent Inorganic Nanocrystals via an Organic Molecular Switch[J]. Phys Chem Chem Phys,2014,16(41):22775-22783.
[33]	Díaz S A,Giordano L, Azc rate J C, et al. Quantum Dots as Templates for Self-Assembly of Photoswitchable Polymers:Small, Dual-Color Nanoparticles Capable of Facile Photomodulation[J]. J Am Chem Soc,2013,135(8):3208-3217.
[34]	Díaz S A, Men ndez G O,Etchehon M H, et al. Photoswitchable Water-Soluble Quantum Dots:pcFRET Based on Amphiphilic Photochromic Polymer Coating[J]. ACS Nano,2011,5(4):2795-2805.
[35]	Díaz S A,Giordano L,Jovin T M,et al.Modulation of a Photoswitchable Dual-Color Quantum Dot Containing a Photochromic FRET Acceptor and an Internal Standard[J]. Nano Lett,2012,12(7):3537-3544.
[36]	Takagi Y,Kunishi T,Katayama T,et al.Photoswitchable Fluorescent Diarylethene Derivatives with Short Alkyl Chain Substituents[J]. Photochem Photobiol Sci,2012,11(11):1661-1665.
[37]	Uno K,Niikura H,Morimoto M,et al.In Situ Preparation of Highly Fluorescent Dyes upon Photoirradiation[J]. J Am Chem Soc,2011,133(34):13558-13564.
[38]	Mao Y,Yi T. Fluorescent Switchable Diarylethene Derivatives and Their Application to the Imaging of Living Cells. In Photon-Working Switches[M]. Yokoyama Y,Nakatani K,Eds. Japan:Tokyo: Springer,2017:133-152.
[39]	Lv G,Cui B,Lan H,et al.Diarylethene Based Fluorescent Switchable Probes for the Detection of Amyloid-β Pathology in Alzheimer's Disease[J]. Chem Commun,2015,51(1):125-128.
[40]	Cao K,Farahi M,Dakanali M,et al.Aminonaphthalene 2-Cyanoacrylate(ANCA) Probes Fluorescently Discriminate Between Amyloid-β and Prion Plaques in Brain[J]. J Am Chem Soc,2012,134(42):17338-17341.
[41]	Liu K,Wen Y,Shi T,et al.DNA Gated Photochromism and Fluorescent Switch in a Thiazole Orange Modified Diarylethene[J]. Chem Commun,2014,50(65):9141-9144.
[42]	Biancardi A,Biver T,Marini A,et al.Thiazole Orange(TO) as a Light-Switch Probe:A Combined Quantum-Mechanical and Spectroscopic Study[J]. Phys Chem Chem Phys,2011,13(27):12595-12602.
[43]	Irie M,Miyatake O,Uchida K. Blocked Photochromism of Diarylethenes[J]. J Am Chem Soc,1992,114(22):8715-8716.
[44]	Mohanty J,Thakur N,Dutta Choudhury S,et al.Recognition-Mediated Light-Up of Thiazole Orange with Cucurbit[8]uril:Exchange and Release by Chemical Stimuli[J]. J Phys Chem B,2012,116(1):130-135.
[45]	Xu Y,Guo M,Li X,et al.Formation of Linear Supramolecular Polymers that is Based on Host-Guest Assembly in Water[J]. Chem Commun,2011,47(31):8883-8885.
[46]	Mao Y,Liu K,Lv G,et al.CB[8] Gated Photochromism of a Diarylethene Derivative Containing Thiazole Orange Groups[J]. Chem Commun,2015,51(30):6667-6670.
[47]	Hu H,Zhu M,Meng X,et al.Optical Switching and Fluorescence Modulation Properties of Photochromic Dithienylethene Derivatives[J]. J Photochem Photobiol A:Chem,2007,189(2):307-313.
[48]	Jing S,Zheng C,Pu S,et al.A Highly Selective Ratiometric Fluorescent Chemosensor for Hg2+ Based on a New Diarylethene with a Stilbene-Linked Terpyridine Unit[J]. Dyes Pigm,2014,107:38-44.
[49]	Yokel R A. Aluminum Chelation Principles and Recent Advances[J]. Coord Chem Rev,2002,228(2):97-113.
[50]	Altschuler E. Aluminum-Containing Antacids as a Cause of Idiopathic Parkinson's Disease[J]. Med Hypotheses,1999,53(1):22-23.
[51]	Li S Y,Zhang D B,Wang J Y,et al.A Novel Diarylethene-Hydrazinopyridine-Based Probe for Fluorescent Detection of Aluminum Ion and Naked-Eye Detection of Hydroxide Ion[J]. Sens Actuators B:Chem,2017,245:263-272.
[52]	Wu J,Sheng R,Liu W,et al.Fluorescent Sensors Based on Controllable Conformational Change for Discrimination of Zn2+ over Cd2+[J]. Tetrahedron,2012,68(27/28):5458-5463.
[53]	Pu S,Zhang C,Fan C,et al.Multi-Controllable Properties of an Antipyrine-Based Diarylethene and Its High Selectivity for Recognition of Al3+[J]. Dyes Pigm,2016,129:24-33.
[54]	Zhang C,Pu S,Sun Z,et al.Highly Sensitive and Selective Fluorescent Sensor for Zinc Ion Based on a New Diarylethene with a Thiocarbamide Unit[J]. J Phys Chem B,2015,119(13):4673-4682.
[55]	Zhang X,Wang R,Fan C,et al.A highly Selective Fluorescent Sensor for Cd2+ Based on a New Diarylethene with a 1,8-Naphthyridine Unit[J]. Dyes Pigm,2017,139:208-217.
[56]	Dong X,Wang R,Liu G,et al.A Novel Sensitive Sensor for Cu2+ and Multi-Switch Based on a Diarylethene with a 2-(2'-Hydroxyphenyl)benzothiazole Unit[J]. Tetrahedron,2016,72(22):2935-2942.
[57]	Li G,Ma L,Liu G,et al.A Diarylethene-Based “On-Off-On” Fluorescence Sensor for the Sequential Recognition of Mercury and Cysteine[J]. RSC Adv,2017,7(33):20591-20596.
[58]	Qu S,Zheng C,Liao G,et al.A Fluorescent Chemosensor for Sn2+ and Cu2+ Based on a Carbazole-Containing Diarylethene[J]. RSC Adv,2017,7(16):9833-9839.
[59]	Xue D,Zheng C,Fan C,et al.A Colorimetric Fluorescent Sensor for Cr3+ Based on a Novel Diarylethene with a Naphthalimide-Rhodamine B Group[J]. J Photochem Photobiol A:Chem,2015,303:59-66.
[60]	Stephens D J,Allan V J. Light Microscopy Techniques for Live Cell Imaging[J]. Science,2003,300(5616):82-86.
[61]	Carreon J R,Stewart K M,Mahon K P,et al.Cyanine Dye Conjugates as Probes for Live Cell Imaging[J]. Biorg Med Chem Lett,2007,17(18):5182-5185.
[62]	Negre-Salvayre A,Aug N,Duval C,et al.[5] Detection of Intracellular Reactive Oxygen Species in Cultured Cells Using Fluorescent Probes[J]. Methods Enzymol,2002,352:62-71.
[63]	Zhu M Q,Zhu L,Han J J,et al.Spiropyran-Based Photochromic Polymer Nanoparticles with Optically Switchable Luminescence[J]. J Am Chem Soc,2006,128(13):4303-4309.
[64]	Wiedenmann J,Ivanchenko S,Oswald F,et al.EosFP, a Fluorescent Marker Protein with UV-Inducible Green-to-Red Fluorescence Conversion[J]. Proc Natl Acad Sci USA,2004,101(45):15905-15910.
[65]	Zhang J,Campbell R E,Ting A Y,et al.Creating New Fluorescent Probes for Cell Biology[J]. Nat Rev Mol Cell Biol,2002,3(12):906-918.
[66]	Zhu M-Q,Zhang G-F,Li C,et al.Reversible Two-Photon Photoswitching and Two-Photon Imaging of Immunofunctionalized Nanoparticles Targeted to Cancer Cells[J]. J Am Chem Soc,2011,133(2):365-372.
[67]	Soh N,Yoshida K,Nakajima H,et al.A Fluorescent Photochromic Compound for Labeling Biomolecules[J]. Chem Commun,2007,(48):5206-5208.
[68]	Piao X,Zou Y,Wu J,et al.Multiresponsive Switchable Diarylethene and Its Application in Bioimaging[J]. Org Lett,2009,11(17):3818-3821.
[69]	Jae Lee M,Ho Kang S. Photoswitchable Fluorescent Diarylethene in a Turn-On Mode for Live Cell Imaging[J]. Chem Commun,2012,48(31):3745-3747.
[70]	Wang S,Li C P,Xu L,et al.A Photochromic Fluorescent Probe for Hg2+ Based on Dithienylethene-Rhodamine B Dyad and Its Application in Live Cells Imaging[J]. Sci Adv Mater,2017,9(3/4):533-540.
[71]	Al-Atar U,Fernandes R,Johnsen B,et al.A Photocontrolled Molecular Switch Regulates Paralysis in a Living Organism[J]. J Am Chem Soc,2009,131(44):15966-15967.
[72]	Huang B,Wang W,Bates M,et al. Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy[J]. Science,2008,319](5864):810-813.
[73]	Heilemann M,Dedecker P,Hofkens J,et al.Photoswitches:Key Molecules for Subdiffraction-Resolution Fluorescence Imaging and Molecular Quantification[J]. Laser Photonics Rev,2009,3(1/2):180-202.
[74]	Tian Z,Wu W, Li A D Q. Photoswitchable Fluorescent Nanoparticles:Preparation, Properties and Applications[J]. Chemphyschem,2009,10(15):2577-2591.
[75]	Tian Z,Li A D Q,Hu D. Super-resolution Fluorescence Nanoscopy Applied to Imaging Core-Shell Photoswitching Nanoparticles and Their Self-Assemblies[J]. Chem Commun,2011,47(4):1258-1260.
[76]	Hua Q X,Xin B,Xiong Z,et al.Super-Resolution Imaging of Self-Assembly of Amphiphilic Photoswitchable Macrocycles[J]. Chem Commun,2017,53(18):2669-2672.
[77]	Gong W L,Xiong Z J,Xin B,et al.Twofold Photoswitching of NIR Fluorescence and EPR Based on the PMI-N-HABI for Optical Nanoimaging of Electrospun Polymer Nanowires[J]. J Mater Chem C,2016,4(13):2498-2505.
[78]	Yan J,Zhao L X,Li C,et al.Optical Nanoimaging for Block Copolymer Self-Assembly[J]. J Am Chem Soc,2015,137(7):2436-2439.
[79]	Zhu M Q,Zhang G F,Hu Z,et al.Reversible Fluorescence Switching of Spiropyran-Conjugated Biodegradable Nanoparticles for Super-Resolution Fluorescence Imaging[J]. Macromolecules,2014,47(5):1543-1552.
[80]	Gong W,Xiong Z,Zhu M. Current Progress in Molecular Photoswitches Based on Hexaarylbiimidazole:Molecular Design and Synthesis, Properties and Application[J]. Imaging Sci Photochem,2014,32(1):43-59.
[81]	Zhang G,Chen T,Li C,et al.Spiropyran-Based Molecular Photoswitches[J]. Chinese J Org Chem,2013,33(5):927-942.
[82]	Li C,Gong W L,Hu Z,et al.Photoswitchable Aggregation-Induced Emission of a Dithienylethene-Tetraphenylethene Conjugate for Optical Memory and Super-Resolution Imaging[J]. RSC Adv,2013,3(23):8967-8972.
[83]	Betzig E,Patterson G H,Sougrat R,et al.Imaging Intracellular Fluorescent Proteins at Nanometer Resolution[J]. Science,2006,313(5793):1642-1645.
[84]	Rust M J,Bates M,Zhuang X. Sub-Diffraction-Limit Imaging by Stochastic Optical Reconstruction Microscopy (STORM)[J]. Nat Methods,2006,3(10):793-796.
[85]	Yan J,Zhao L X,Li C,et al.Optical Nanoimaging for Block Copolymer Self-Assembly[J]. J Am Chem Soc,2015,137(7):2436-2439.
[86]	Gong W L,Yan J,Zhao L X,et al.Single-Wavelength-Controlled in Situ Dynamic Super-Resolution Fluorescence Imaging for Block Copolymer Nanostructures via Blue-Light-Switchable FRAP[J]. Photochem Photobiol Sci,2016,15(11):1433-1441.
[87]	Gong W L,Hu Z,Li C,et al.Condensed State Fluorescence Switching of Hexaarylbiimidazole-Tetraphenylethene Conjugate for Super-Resolution Fluorescence Nanolocalization[J]. Front Optoelectron,2013,6(4):458-467.
[88]	Roubinet B,Weber M,Shojaei H,et al.Fluorescent Photoswitchable Diarylethenes for Biolabeling and Single-Molecule Localization Microscopies with Optical Superresolution[J]. J Am Chem Soc,2017,139(19):6611-6620.
[89]	Arai Y,Ito S,Fujita H,et al.One-Colour Control of Activation, Excitation and Deactivation of a Fluorescent Diarylethene Derivative in Super-Resolution Microscopy[J]. Chem Commun,2017,53(29):4066-4069.
[90]	Nevskyi O,Sysoiev D,Oppermann A,et al.Nanoscopic Visualization of Soft Matter Using Fluorescent Diarylethene Photoswitches[J]. Angew Chem Int Ed,2016,55(41):12698-12702.

Research Progress on Hydrophilic Photoswitchable Fluorescent Diarylethenes

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