Chinese Journal of Applied Chemistry ›› 2022, Vol. 39 ›› Issue (1): 99-109.DOI: 10.19894/j.issn.1000-0518.210484

• Review • Previous Articles     Next Articles

Research Progress of Artificial Water Channels Inspired by Aquaporin

HUAI Meng-Jiao,LIU Tao-Xue-Ting,JIANG Zhong-Yi()   

  1. School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China
  • Received:2021-09-28 Accepted:2021-11-04 Published:2022-01-01 Online:2022-01-10
  • Contact: Zhong-Yi JIANG
  • About
  • Supported by:
    the National Natural Science Foundation of China(91934302);the Key K&D Project of Zhejiang Province(2021C03173)


Based on the structure and functions of aquaporin (AQP), bioinspired and biomimetic membranes that incorporate biological transport channels or their structure mimics have undergone a remarkable development over the last decade. By transplanting the mass transport properties of aquaporins, artificial water channels (AWC) exhibit both high permeability and selectivity. Through the in-depth analysis of AQP, with the aim of both high selectivity and high permeability in the artificial water channel, three types of effects including “gating effect”, “hydrophilic effect” and “queuing effect” are proposed. Then, we analyze and summarize the existing research work of bioinspired desalination membrane. Finally, it is pointed out that the above three effects explore novel paths to the ration design of artificial water channel on account of biomimeticism and bioinspiration philosophy.

Key words: Aquaporin, Biomimetic membrane of desalination, Gating effect, Hydrophilic effect, Queuing effect

CLC Number: