Research Pregress on Synthesis of Xanthene Dyes

doi:10.11944/j.issn.1000-0518.2017.12.170308

Chinese Journal of Applied Chemistry ›› 2017, Vol. 34 ›› Issue (12): 1403-1412.DOI: 10.11944/j.issn.1000-0518.2017.12.170308

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Research Pregress on Synthesis of Xanthene Dyes

LUO Xiao,HE Haihong,YANG Youjun()

State Key Laboratory of Bioreactor Engineering; Shanghai Key Laboratory of Chemical Biology,East China University of Science and Technology,Shanghai 200237,China

Received:2017-08-31 Accepted:2017-09-28 Published:2017-12-04 Online:2017-12-04
Contact: YANG Youjun
Supported by:
Supported by the National Natural Science Foundation of China(No.21372080, No.21572061)

Abstract

Abstract:

Xanthene dyes are a series of brilliant fluorescent dyes exhibiting superior photophysical properties, which facilitate their applications in various field. Traditionally, they are prepared via acid-catalyzed condensations between electron-rich resorcinol(m-aminophenols) and phthalic anhydride. Recently, structurally complicated xanthenes are often in need for bioimaging applications and not readily accessed with the aforementioned methods. This has promoted the development of novel pathways for their synthesis, which are summarized in this review. The scope and limitations of each methods are briefly discussed.

Key words: xanthene, synthesis, fluorophores, molecular probes

LUO Xiao,HE Haihong,YANG Youjun. Research Pregress on Synthesis of Xanthene Dyes[J]. Chinese Journal of Applied Chemistry, 2017, 34(12): 1403-1412.

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Research Pregress on Synthesis of Xanthene Dyes

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