静电纺纳米复合纤维柔性表面增强拉曼散射传感基底的研究进展

doi:10.11944/j.issn.1000-0518.2020.12.200180

摘要/Abstract

摘要： 表面增强拉曼散射(Surface enhanced Raman scattering,SERS)是一种分子检测光谱技术,借助SERS基底,可对生物、化学等复杂体系中的痕量分子进行分析。其中静电纺纳米纤维SERS基底由于具有高比表面积、可透气透水、柔韧可折叠弯曲等特点,在复杂体系中提取、过滤、浓缩痕量分子等应用场景中,其表面结构具有其他刚性SERS基底不可比拟的优势。然而,静电纺纳米纤维SERS基底的发展却受到制备方法的限制,存在检测灵敏度较低、制备过程复杂等问题。因此,目前的研究工作主要集中在新型制备方法及工艺的开发。本文综述了静电纺纳米金银复合纤维SERS基底的几种常用制备方法,包括直接混合纺丝法、化学吸附法、静电吸附法、物理沉积法和原位化学还原法,并总结了静电纺纳米纤维SERS基底在复杂体系中提取、过滤、浓缩待测分子的应用,最后对静电纺纳米复合纤维SERS基底的发展进行了展望。

关键词: 表面增强拉曼散射, 纳米纤维膜, 静电纺丝, 金属纳米粒子

Abstract: Surface enhanced Raman scattering (SERS) is a molecular detection spectroscopy technique. With the help of the SERS substrate, trace molecules in complex systems such as biology and chemistry can be analyzed. Among them, the electrospun nanofiber SERS substrate has the characteristics of high specific surface area, air permeability, water permeability, flexibility, foldability and bending. In the application scenarios of extracting and detecting trace molecules in complex systems, its surface structure has unmatched by other rigid SERS substrates. However, the development of electrospun nanofiber SERS substrates is limited by the preparation method, which has the problems of low detection sensitivity and complicated preparation process. Therefore, the current research work mainly focuses on the development of new preparation methods and processes. This article reviews several common preparation methods for SERS substrates of electrospun nano-gold-silver composite fibers, including direct mixed spinning, chemical adsorption, electrostatic adsorption, physical deposition, and in-situ chemical reduction, and summarizes the application of electrospinning nanofiber SERS substrate in the extraction, filtration and concentration of molecules to be tested in complex systems, and finally the prospect of the development of electrospun nano-composite fiber SERS substrate.

Key words: surface enhanced Raman scattering, nanofiber membrane, electrospinning, metal nanoparticles

中图分类号:

O652

张亮, 贺辛亥, 任研伟, 陈彤善, 陈东圳. 静电纺纳米复合纤维柔性表面增强拉曼散射传感基底的研究进展[J]. 应用化学, 2020, 37(12): 1364-1373.

ZHANG Liang, HE Xinhai, REN Yanwei, CHEN Tongshan, CHEN Dongzhen. Electrospinning Composite Nanofibers for the Application of Flexible Substrate of Surface-Enhanced Raman Scattering Sensing[J]. Chinese Journal of Applied Chemistry, 2020, 37(12): 1364-1373.

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