三唑Schiff碱邻甲酰胺基苯甲酰胺衍生物的合成及生物活性

doi:10.3724/SP.J.1095.2014.40035

摘要/Abstract

摘要： 以2,4-二氯苯甲酸和2-氨基-3-甲基苯甲酸为起始原料，设计合成了8个新型含2,4-二氯苯基1,2,4-三唑Schiff碱邻甲酰胺基苯甲酰胺类化合物，通过1H NMR、IR及元素分析等技术手段对目标化合物进行了结构表征。采用Airbrush喷雾法进行生物活性测试，结果表明，部分化合物具有不同程度的杀虫活性,其中化合物9a在600 mg/L浓度下对小菜蛾和粘虫的致死率均为100%。

关键词: 邻甲酰胺基苯甲酰胺, 二氯苯基, 三唑, 合成, 生物活性

Abstract: Using 2,4-dichlorobenzoic acid and 2-amino-3-methylbenzoic acid as starting materials, eight novel anthranilic diamide derivatives containing 1,2,4-triazole Schiff base and 2,4-dichlorophenyl unit were synthesized. The structures were confirmed by 1H NMR, IR and elemental analysis. The preliminary bioassay showed that compound 9a has significant insecticidal activity with 100% inhibition of Leucania separata and Plutella xylostella at 600 mg/L.

Key words: anthranilic diamide, dichlorophenyl, triazole, synthesis, biological activity

中图分类号:

O626.2

郑玉国, 宋泽斌, 宋松, 李仲明, 邓钊, 吴用, 付如凯, 黄勇, 郭晴晴. 三唑Schiff碱邻甲酰胺基苯甲酰胺衍生物的合成及生物活性[J]. 应用化学, DOI: 10.3724/SP.J.1095.2014.40035.

ZHENG Yuguo*, SONG Zebin, SONG Song, LI Zhongming, DENG Zhao, WU Yong, FU Rukai, HUANG Yong, GUO Qingqing. Synthesis and Biological Activity of Novel Anthranilic Diamide Derivatives Containing 1,2,4-Triazole Schiff Base[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2014.40035.

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