Synthesis, Biological Activity and Electrochemical Properties of Ferrocenyl 1,3,4-Triazoles Derivatives

doi:10.3724/SP.J.1095.2014.30294

Chinese Journal of Applied Chemistry

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Synthesis, Biological Activity and Electrochemical Properties of Ferrocenyl 1,3,4-Triazoles Derivatives

ZHU Chang'an, WU Feiyu, WANG Xue, GAO Li′na, WENG Qianfeng, SHI Li, ZHANG Chenglu^*

(School of Chemistry and Chemical Engineering,Liaoning Normal University,Dalian 116029,China)

Received:2013-06-13 Revised:2013-09-18 Published:2014-04-10 Online:2014-04-10
Contact: zhang
About author:Zhang Chenglu, Professor, Tel：13889649719；Email：zhangchenglu@lnnu.edu.cn；Research interests：drug synthesis

Abstract

Abstract: Ferrocenyl-1,3,4-triazoles Schiff base derivatives（5a~5e）were synthesized and characterized by IR, 1H NMR and HRMS for the first time. The cell division activity and auxin activity were tested by cucumber cotyledon method and wheat malt sheath method. At a concentration of 10 mol/L, four compounds show 46.9%~73.6％ promoting activity which is higher than that of the control. The auxin activity of compound 5c is up to 25％. The herbicidal activities of the compounds are up to 68%~72%. Cyclic voltammetry was used to detect the electrochemical behavior of the target compounds using glassy carbon electrode modified with graphene in the Britton-Robison buffer solution. The influence of pH, potential scanning rate and concentration on the electrochemical behavior of the target compounds was studied. These compounds perform good redox reversibility when pH value is equal to 2 or 3. The logarithm of oxidation peak current(Ipc) shows good linear relationship with the logarithm of scanning rate and the logarithm of concentration. The electron transfer of compounds（5a~5d） is reversible process under control of adsorption-diffusion. The lowest of detection is 10-5 mol/L.

Key words: ferrocenyltriazole, plant growth regulatory activity, herbicide activity, cyclic voltammetry

CLC Number:

O626

ZHU Chang'an, WU Feiyu, WANG Xue, GAO Li′na, WENG Qianfeng, SHI Li, ZHANG Chenglu*. Synthesis, Biological Activity and Electrochemical Properties of Ferrocenyl 1,3,4-Triazoles Derivatives[J]. Chinese Journal of Applied Chemistry, DOI: 10.3724/SP.J.1095.2014.30294.

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Synthesis, Biological Activity and Electrochemical Properties of Ferrocenyl 1,3,4-Triazoles Derivatives

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