Abstract:

The silver doped poly(L-aspartic acid) modified electrode was prepared by cyclic voltammetric method, and the voltammetric behavior of epinephrine and cyclic voltammetric method determination of epinephrine were studied at the silver doped poly(L-aspartic acid) modified electrode. In pH3.5 phosphate buffer solution, the peak potential of epinephrine were 0.447V of Epa and 0.387 V of Epc (νs Ag/AgCl) at the scan rate 50 mV/s. The linear range for the determination of epinephrine were 8.0×10-8~1.0×10-5 mol/L and 1.0×10-5~1.0×10-4 mol/L. The detection limit was 8.0×10-9 mol/L. This method was applied to the determination of epinephrine in drug and urine with satisfactory results.

Key words: epinephrine, L-aspartic acid, silver doped, modified electrode, cyclic voltammetry