Solvent-Solute Interaction between Hydrocortisone and Organic Solvents

Chinese Journal of Applied Chemistry ›› 1998, Vol. 0 ›› Issue (1): 41-43.

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Solvent-Solute Interaction between Hydrocortisone and Organic Solvents

Tang Zhigang, Hu Xi'en, Zhu Yongjun

Institute of Nuclear Energy Technology, Tsinhua University, Beijing 100084

Received:1997-04-02 Revised:1997-08-15 Published:1998-02-10 Online:1998-02-10

Abstract

Abstract: The distribution coefficients of hydrocortisone in some solvent/water systems in-dicate that hydrocortisone has a stronger hydrogen bonds with alcohols and ketones, butcomparatively weak hydrogen bonds with esters, ethers and chlorocarbons.Hydrocortisonecan hardly form hydrogen bonding interaction with tetrachloromethane, benzene, and cyclo-hexane.

Key words: hydrocortisone, solvent-solute interaction, hydrogen bond, distribution coefficient

Tang Zhigang, Hu Xi'en, Zhu Yongjun. Solvent-Solute Interaction between Hydrocortisone and Organic Solvents[J]. Chinese Journal of Applied Chemistry, 1998, 0(1): 41-43.

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Solvent-Solute Interaction between Hydrocortisone and Organic Solvents

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