Synthesis and Bioactivity of Some 2-Thiophosphate-3,4-Dihydrofuroquinolines

Chinese Journal of Applied Chemistry ›› 1996, Vol. 0 ›› Issue (5): 14-16.

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Synthesis and Bioactivity of Some 2-Thiophosphate-3,4-Dihydrofuroquinolines

Liu Zhun, Li Shuzheng, Mi Zhongmao, Zhang Chunxiang, Sun Ying

Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071

Received:1995-11-23 Revised:1996-05-17 Published:1996-10-10 Online:1996-10-10

Abstract

Abstract: Ten new title compounds were synthesized by condensation of thiophosphoryl chlorides and 2-sodium alcoholate-6-substitutent-3, 4-dihydrofuroquinolines, the latter being prepared from the reduction of corresponding 2-oxo compounds with sodium hydride. Their structures were confirmed by ¹H NMR, MS, and elemental analysis. Some of them have good antifungous activity to pellicularia sasakii of rice.

Key words: synthesis, dihydrofuroquinoline, thiophosphate, antifungous activity

Liu Zhun, Li Shuzheng, Mi Zhongmao, Zhang Chunxiang, Sun Ying. Synthesis and Bioactivity of Some 2-Thiophosphate-3,4-Dihydrofuroquinolines[J]. Chinese Journal of Applied Chemistry, 1996, 0(5): 14-16.

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Synthesis and Bioactivity of Some 2-Thiophosphate-3,4-Dihydrofuroquinolines

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