STUDIES ON ACYLTHIOSEMICARBAZIDES AND RELATED HETEROCYCLIC DERIVATIVES ⅩⅤ.SYNTHESIS AND ANTIBACTERIAL ACTION OF 3-(5-(3-PYRIDYL)-2H-TETRAZOL-2-YLMETHYL)-4-ARYL-1,2,4-TRIAZOL-5-ALKYLSULFIDE

Chinese Journal of Applied Chemistry ›› 1990, Vol. 0 ›› Issue (5): 27-33.

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STUDIES ON ACYLTHIOSEMICARBAZIDES AND RELATED HETEROCYCLIC DERIVATIVES ⅩⅤ.SYNTHESIS AND ANTIBACTERIAL ACTION OF 3-(5-(3-PYRIDYL)-2H-TETRAZOL-2-YLMETHYL)-4-ARYL-1,2,4-TRIAZOL-5-ALKYLSULFIDE

Chen Limin¹, Zhang Ziyi¹, Wu Heping¹, Zheng Guoyu²

1. Department of Chemistry, Lanzhou University, Lanzhou 730000;
2. Department of Biology, Lanzhou University, Lanzhou, Lanzhou 730000

Received:1989-10-30 Revised:1990-03-23 Published:1990-10-10 Online:1990-10-10

Abstract

Abstract: Nineteen 3-(5-(3-pyridyl)-2H-tetrazol-2-ylmethyl)-4-aryl-1, 2, 4-triazol-5-alkylsulfidesfrom 3-(5-(3-pyridyl)-2H-tetrazol-2-ylmethyl)-4-aryl-1, 2, 4-triazol-5-thione were prepared.Their structures were characterized by elemental analysis, IR,HNMR,MS. Antibactericidalactivity test of these compounds against E. Coli, A. Aerogenes, B. Subtilis, and S. Aureusshowed that compounds 3_a-kare the most effective species.

Key words: acylthiosemicarbazides, triazol alkylsulfide, antibacterial activity

Chen Limin, Zhang Ziyi, Wu Heping, Zheng Guoyu. STUDIES ON ACYLTHIOSEMICARBAZIDES AND RELATED HETEROCYCLIC DERIVATIVES ⅩⅤ.SYNTHESIS AND ANTIBACTERIAL ACTION OF 3-(5-(3-PYRIDYL)-2H-TETRAZOL-2-YLMETHYL)-4-ARYL-1,2,4-TRIAZOL-5-ALKYLSULFIDE[J]. Chinese Journal of Applied Chemistry, 1990, 0(5): 27-33.

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STUDIES ON ACYLTHIOSEMICARBAZIDES AND RELATED HETEROCYCLIC DERIVATIVES ⅩⅤ.SYNTHESIS AND ANTIBACTERIAL ACTION OF 3-(5-(3-PYRIDYL)-2H-TETRAZOL-2-YLMETHYL)-4-ARYL-1,2,4-TRIAZOL-5-ALKYLSULFIDE

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