Chinese Journal of Applied Chemistry ›› 1989, Vol. 0 ›› Issue (5): 59-62.

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SYNTHESIS OF β-(PHENOLESTER)ETHYLGERMANIUM SESQUIOXIDES AND THEIR EFFECTS ON CELLS IN VITRO

Shangguan Guoqiang1, Zhang Shugong1, Ni Jiazuan1, Nie Yuxiu2   

  1. 1. Changchun Institute of Applied Chemistry, Academia Sinica;
    2. Norman Bethune University of Medical Science, Changchun
  • Received:1988-10-15 Revised:1989-03-11 Published:1989-10-10 Online:1989-10-10

Abstract: Eight compounds of (GeCH2CH2COOAr)2O3 type were synthesized. Their constitutesand structures were determined by elemental analysis and IR specrophotometry. Three ofthem were tested for antitumour activities against Hela cells in vitro, showing some tumourinhibitory activity. Their effects on diploid cell were not obvious in mitosis and shape.

Key words: Organogermanium compound, Synthesis, Antitumour activity