Abstract:

Polymeric HAP/P(MMA-St) composite microspheres were synthesized via suspension polymerization with microporous hydroxyl apatite(HAP) nanomaterial as inorganic carrier, polymethyl methacrylate(MMA) and styrene(St) as monomers. The effects of main factors on the particle distribution and adsorption performance of polymeric HAP/P(MMA-St) composite microspheres were investigated. Experimental results show that a maximal yield of qualified microspheres of 86.4% could be achived when the mass fractions of surfactant, MMA and HAP were 10%, 20% and 30% accordingly under a rotation speed of 300 r/min.  The absorbability of polymeric microspheres for BSA was studied through a static adsorption process. When the mass fraction of HAP was 36.07%, adsorption quantity was Qe=18.70 mg/g, an increase of 4.65 mg/g could be observed compared to that without adding.

Key words: HAP, MMA, St