Chinese Journal of Applied Chemistry ›› 2009, Vol. 26 ›› Issue (07): 786-790.

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Preparation of resveratrol molecularly imprinted composite membranes and its selectivity to the template

  

  • Received:2008-07-04 Revised:2008-10-30 Online:2009-07-10 Published:2009-07-10

Abstract: Using trans-resveratrol(RES) as template molecule , acrylamide(AA) as functional monomer and ethyleneglycol dimethacrylate (EDMA ) as the cross-linking agent, the molecularly imprinted membranes ,with polyvinylidene fluoride microporous membrane as supporting membrane,were synthesized throuth in situ polymerization by thermal initiation. Scanning electron microscope (SEM) were used to visualize surface of membranes.The binding ability and permeation selectivity were studied for RES and its analogues ,polydatin(POL),bisphel A(BPA) and 2-naphthol. The results showed that the imprinted membranes demonstrated satisfactory recognition capacity and selectivity towards the template.Rebinding of RES was much higher than that of structurally similar compounds.The saturated binding capacity of the imprinted composite membrane for RES is about 1.72μmol/g, nearly 3 times of that of non-imprinted polymer membrane. Both the size effect and the imprining effect contributed to the permeation performances. 2-Naphthol , which is smaller than the template in size, preferentially transports through the the imprinted composite membrane because of the size effect. The permeation flux of RES is higher than that of BPA ,with the same size to the template, and POL , bigger than the template, through the imprinted membrane, due to its complementary functional group s and shape with the imprinted sites on the the imprinted composite membrane. The RES transfer rate increased for the imprinted composite membranes due to the larger amount of binding sites, comparing with the non-imprinted one.

Key words: resveratrol, molecularly imprinted composite membrane, selectivity, binding and permeation property