Abstract: α-Methyl pyrazones have been reacted with aryl diazonium salts to form 3-arylhy-drazones-6-methyl-2,4-dioxopyranones,which are converted to 1-aryl-6-methyl-4-oxo-pyri-dazinone-3-carboxylic acids by cyclization. A series of 4-pyridazinone-3-amides were obtained by reacting the carboxylic acids with ethylchlorocarboxylate and corresponding amines. The structures of new compounds thus obtained were checked by elemental analyses,IR,NMR and MS measurements.

Key words: pyridazinone, chemical induction agent of male sterility, synthesis