Abstract:

Crosslinked polystyrene microspheres(CPS) were first chloromethylated with noncarcinogenic 1,4-bis(chloromethoxy)butane(BCMB) to form chloromethylated microspheres(CMCPS). Then quaternization reaction between CMCPS microspheres and 4-pyridylaldehyde was carried out to modify the CPS microspheres with 4-pyridylaldehyde(PyAL-CPS). The effects of main factors on the quaternization reaction were examined, and the synthetic conditions were optimized. The suitable temperature and appropriate solvent are 60 ℃ and CCl4, respectively. Finally, Alder reaction at the interface of solid/solution between 4-pyridylaldehyde on the surface of modified microspheres and pyrrole was performed to form the functional microspheres(PyP-CPS), on which the formation of pyridyl porphyrin(PyP) could be achieved. The PyP-CPS formation were characterized by using IR and UV-Vis while and the loading of PyP was demonstrated by forming Zn-PyP complex.

Key words: crosslinked polystyrene microsphere, pyridylaldehyde, quaternization reaction, pyridyl porphyrin, immobilization