Preparation of Regenerated Cellulose Microspheres and Their Adsorption of Methylene Blue and Loading of Folic Acid

doi:10.19894/j.issn.1000-0518.240073

Chinese Journal of Applied Chemistry ›› 2024, Vol. 41 ›› Issue (10): 1445-1456.DOI: 10.19894/j.issn.1000-0518.240073

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Preparation of Regenerated Cellulose Microspheres and Their Adsorption of Methylene Blue and Loading of Folic Acid

Xing-Yi LIANG¹^,², Ya LI²(), Jing-Tian XUN², Wei-Wei ZHANG¹, Chang-Zi JIN¹, Rui WANG¹, Dan QIU¹^,², Yu-Peng HE¹^,³

^1.School of Petrochemical Engineering，Liaoning Petrochemical University，Fushun 113001，China
^2.School of Materials and Chemical Engineering，Ningbo University of Technology，Ningbo 315211，China
^3.Ningbo Research Institute，Dalian University of Technology，Ningbo 315016，China

Received:2024-03-06 Accepted:2024-09-13 Published:2024-10-01 Online:2024-10-29
Contact: Ya LI
About author:liya@nbut.edu.cn
Supported by:
Ningbo Natural Science Foundation(2019C10037)

Abstract

Abstract:

Regenerate cellulose microspheres （RCM） with different particle sizes are prepared by an emulsion method， a urea/NaOH solution of microcrystalline cellulose （MCC） was used as the dispersant phase. Both the adsorption behavior of RCM for methylene blue and its and the loading performance for folic acid （FA） is investigated. Scanning electron microscopy （SEM） results reveal that the prepared RCM has a rough surface structure and exhibits a certain degree of internal hollow structure. X-ray diffraction （XRD） and Fourier transform infrared spectrometer （FT-IR） analyses indicate a transition in crystal type from type Ⅰ to type Ⅱ of cellulose. The particle size of RCM decreased as the rotation speed increased， diminishing by approximately 90.56% from 286 to 27 μm when the rotation speed rised from 400 to 1200 r/min. Additionally， decreasing V（MCC）∶V（LP） from 1∶3 to 1∶7 leads to a reduction in particle size by about 82.64%， decreasing from 311 to 54 μm. Furthermore， increasing emulsifier （w（span-80）） dosage results in the decrease of particle size. The particle size is around 276 μm at w（span-80） of 0.5%， which decreased to approximately 52 μm as w（span-80） increasing up to 2.5%. The adsorption of methylene blue reached equilibrium at 72 h. The maximum adsorption capacity occurs at pH=10 with an up take value of 6.11 mg/g. When the dosage of RCM is 50 mg， the maximum sorption capacity reaches 4.78 mg/g. The adsorption process is primarily surface-based according to the hypothetical first-order adsorption kinetics of RCM. For RCM loading FA microspheres on， a specific loading rate as high as 98.8% can be achieved. The application of regenerated cellulose-loaded FA microspheres effectively improves the storage stability of FA with a retention rate of 74.71% 5 days storage at 70 ℃， showing an increase of 34.7% compared to pure FA.

Key words: Regenerated cellulose, Microspheres, Adsorption, Methylene blue, Folic acid

CLC Number:

O636

Xing-Yi LIANG, Ya LI, Jing-Tian XUN, Wei-Wei ZHANG, Chang-Zi JIN, Rui WANG, Dan QIU, Yu-Peng HE. Preparation of Regenerated Cellulose Microspheres and Their Adsorption of Methylene Blue and Loading of Folic Acid[J]. Chinese Journal of Applied Chemistry, 2024, 41(10): 1445-1456.

Figures/Tables 11

Fig.1 SEM images of RCM prepared with different V（MCC）∶V（LP） and XRD pattern of MCC （speed 800 r/min， w（span-80）=2%）

Fig.2 FT-IR spectra of MCC and RCM

Fig.3 SEM images of RCM prepared at speeds of 400 （A）， 600 （B）， 800 （C）， 1000 （D） and 1200 r/min （E） and the effect of speed on particle size （F）（V（MCC）∶V（LP）=1∶5， w（span-80）=2%）

Fig.4 SEM images of regenerated cellulose microspheres prepared at V（MCC）∶V（LP）=1∶3 （A）， 1∶4 （B）， 1∶5 （C）， 1∶6 （D） and 1∶7 （E） and the effect of water-oil ratio on particle size （F）（speed 800 r/min， w（span-80）=2%）

Fig.5 SEM images of RCM prepared at w（span-80） is 0.5% （A）、1% （B）、1.5% （C）、2% （D）、2.5% （E） and the effect of emulsifier dosage on particle size （F）（speed 800 r/min， V（MCC）∶V（LP）=1∶5）

Fig.6 The influence of adsorption time （A）， pH （B） and the amount of RCM （C）， on the MB adsorption capacity of regenerated cellulose microspheres and the change of adsorption （D）

Fig.7 Effect of RCM particle size on RCM （A）； Linear fitting curves for the Pseudo-First-Order kinetic model （B）； Linear fitting curves for the Pseudo-Second-Order kinetic model （C）

Table 1 Dynamic model equations and related parameters

RCM particle size/μm	Dynamical model	Equation	k	q_e	R²
27	pseudo-first-order model	lg（q_e-q_t ）=0.5546-0.0265t	0.060 96	3.585 9	0.916 2
27	pseudo-second order reaction	t/q_t =810.3-13.92t	0.239 4	0.071 8	0.428 6
153	pseudo-first-order model	lg（q_e-q_t ）=0.7367-0.0242t	0.055 78	5.453 8	0.838 4
153	pseudo-second order reaction	t/q_t =814.91-14.15t	0.246 2	0.070 6	0.438 1
311	pseudo-first-order model	lg（q_e-q_t ）=0.4423-0.02391t	0.055 06	2.769 1	0.835 5
311	pseudo-second order reaction	t/q_t =98.14-1.055t	0.111 3	0.947 9	0.367 4

Fig.8 FT-IR spectra of FA loaded on RCM

Fig.9 XRD spectra of FA loaded on RCM

Fig.10 Diagram of FA loading capacity varying with time （A）； Changes in FA content with time in FA raw materials and FA loaded onto RCM samples （B）

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Preparation of Regenerated Cellulose Microspheres and Their Adsorption of Methylene Blue and Loading of Folic Acid

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