Application of Protein Microarray in Clinical Analsis

doi:10.11944/j.issn.1000-0518.2016.11.160315

Chinese Journal of Applied Chemistry ›› 2016, Vol. 33 ›› Issue (11): 1253-1264.DOI: 10.11944/j.issn.1000-0518.2016.11.160315

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Application of Protein Microarray in Clinical Analsis

LI Zhuheng^a^b,LIU Xia^b,LIU Dianjun^b,WANG Zhenxin^b^*()

^aJilin Provincial Institute of Education,Changchun 130024,China
^bState Key Laboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China

Received:2016-08-10 Accepted:2016-09-20 Published:2016-11-01 Online:2016-11-01
Contact: WANG Zhenxin
Supported by:
Supported by the National Natural Science Foundation of China(No.21475126)

Abstract

Abstract:

Protein microarray is capable of high-throughput monitoring biological toxins, analyzing the host-microbe interactions and the antigen-antibody interaction, and screening biomarkers of diseases. Therefore, protein microarray is expected to become one of the main technology of in vitro diagnostic and plays an important role in precision medicine of many diseases, such as pathogen infection, autoimmune diseases, neurodegenerative diseases, cancer and so on. Through analyzing the recently published research results, this review summarizes recent progress of protein microarray in the clinical analysis, analyzes the technical challenges in practical application, and discusses corresponding solutions.

Key words: protein microarray, clinical detection, high-throughput analysis, biological molecular interaction

LI Zhuheng,LIU Xia,LIU Dianjun,WANG Zhenxin. Application of Protein Microarray in Clinical Analsis[J]. Chinese Journal of Applied Chemistry, 2016, 33(11): 1253-1264.

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Application of Protein Microarray in Clinical Analsis

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