中华医学超声杂志

应用化学

• 研究论文 • 上一篇    下一篇

纳米镍修饰TiO2纳米管电极检测胰岛素

张云怀1,董西哲1*,肖鹏2,何辉超1,李小玲1   

  1. (1.重庆大学化工学院 重庆 400030；2.重庆大学物理学院 重庆 400030)
  • 收稿日期:2011-08-25 修回日期:2011-11-01 出版日期:2012-08-10 发布日期:2012-08-10
  • 通讯作者: 董西哲，硕士研究生; Tel/Fax:023-65102031; E-mail:xixizhezhe@126.com; 研究方向：纳米材料的研究

Detection of Insulin by Nickel Nanoparticles Modified Titanium Oxide Nanotube Electrode

ZHANG Yunhuai1, DONG Xizhe1*, XIAO Peng2, HE Huichao1, LI Xiaoling1   

  1. (1.College of Chemistry and Chemical Engineering,Chongqing University,Chongqing 400030,China;
    2.College of Physics,Chongqing University,Chongqing 400030,China)
  • Received:2011-08-25 Revised:2011-11-01 Published:2012-08-10 Online:2012-08-10
  • Contact: DONG Xizhe

PDF

1214

摘要： 采用阳极氧化法制备出高度有序的TiO2纳米管阵列作为基础电极，通过电沉积法将纳米镍颗粒负载在基础电极上，从而制备了纳米镍-二氧化钛纳米管（Ni/TiO2NTs）修饰电极。 分别采用扫描电子显微镜和X射线衍射对Ni/TiO2NTs电极的形貌及组分进行了表征。 将Ni/TiO2NTs电极用于对胰岛素的电化学测定。 结果表明，在0.1 mol/L NaOH支持电解液中，胰岛素在Ni/TiO2NTs电极上有较好的电化学响应，胰岛素浓度在0.8~1.6 μmol/L范围内，峰电流密度与其浓度呈良好的线性关系，检测限为0.28 μmol/L，灵敏度为0.49×10-3 A/(μmol·L-1·cm-2)。

关键词: 电化学, 修饰电极, 纳米镍, TiO2纳米管阵列, 胰岛素

Abstract: Highly ordered TiO2 nanotube arrays(TiO2NTs) fabricated by anodization were employed as a substrate and loaded with Ni nanoparticles by pulse electrodeposition. The morphology and composites of titanium dioxide nanotubes and Ni/TiO2NTs electrodes were investigated using scanning electron microscopy and energy-dispersive X-ray spectroscopy, respectively. The Ni/TiO2NTs was used as an amperometric detector for electrocatalytic oxidation and determination of insulin. The results show that Ni/TiO2NTs electrode enables the oxidative detection of insulin at this modified electrode. The linear dynamic range of the detection is 0.8~1.6 μmol/L in 0.1 mol/L NaOH electrolyte, with a good sensitivity (0.49×10-3 A/(μmol·L-1·cm-2) and low detection limit (0.28 μmol/L).

Key words: electrochemistry, modified electrode, nickel nanoparticles, titanium oxide nanotube arrays, insulin

中图分类号: 

网站版权 © 应用化学     本网站备案：吉ICP备12000082号