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• 研究简报 • 上一篇    

羟丙基-β-环糊精富集提取射干中异黄酮

李美慧,张宇,张森,夏婷婷,郝爱友*   

  1. (山东大学化学与化工学院 济南 250100)
  • 收稿日期:2011-07-18 修回日期:2011-09-24 出版日期:2012-06-10 发布日期:2012-06-10
  • 通讯作者: 郝爱友，教授; Tel:0531-88363306; Fax:0531-8564464; E-mail:haoay@sdu.edu.cn; 研究方向：有机化学
  • 基金资助:
    山东大学2010年度大学生科技创新基金资助项目(2010108)

The Enrichment of Isoflavones in Belamcanda Chinensis Using Hydroxypropyl-β-cyclodextrins

LI Meihui, ZHANG Yu, ZHANG Sen, XIA Tingting, HAO Aiyou*   

  1. (College of Chemistry and Chemical Engineering,Shandong University,Ji′nan 250100)
  • Received:2011-07-18 Revised:2011-09-24 Published:2012-06-10 Online:2012-06-10
  • Contact: HAO Aiyou

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摘要： 利用羟丙基-β-环糊精（HP-β-CD）水溶液对中药射干（Belamcanda chinensis）中功能性成分异黄酮类物质富集提取。 考察了时间、温度等对提取效果的影响，确定了优化的工艺条件；结合紫外光谱、高效液相色谱和液相色谱-质谱联用等检测手段，测定提取源总异黄酮含量及黄酮种类。 在此条件下，对异黄酮类物质的提取总量较纯水浸取提高1倍，鸢尾苷提取量可提高2倍。

关键词: 羟丙基-&, beta, -环糊精, 射干, 异黄酮, 鸢尾苷

Abstract: Hydroxypropyl-β-cyclodextrins were applied to extract and enrich isoflavones which is the functional material in Belamcanda chinensis. The extracting time and temperature were studied and the process was optimized. The amount and the category of the extrtacted isoflavones were characterized by means of UV-Vis, HPLC and HPLC-MS. Under optimized conditions, the extracting amount of isoflavones was 2 times and the extracting amount of tectoridin was 3 times as those using water as the extractant. The as-established methodology is promising to be extended to the extraction research technology of Chinese traditional drugs.

Key words: hydroxypropyl-&, beta, -cyclodextrins, Belamcanda chinensis, isoflavones, tectoridin

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