中华医学超声杂志

应用化学 ›› 1990, Vol. 0 ›› Issue (2): 69-70.

• 研究简报 • 上一篇    下一篇

苯乙烯的相转移催化溴-羟基化

颜世刚, 宋树忠   

  1. 中国科学院大连化学物理研究所 大连 116012
  • 收稿日期:1989-05-20 修回日期:1989-08-17 出版日期:1990-04-10 发布日期:1990-04-10

PHASE TRANSFER CATALYZED BROMO-HYDROXYLATION OF STYRENE

Yan Shigang, Song Shuzhong   

  1. Dalian Institute of Chemical Physics, Academia Sinica, Dalian116012
  • Received:1989-05-20 Revised:1989-08-17 Published:1990-04-10 Online:1990-04-10

PDF

319

被引次数

1

摘要： β-苯乙醇是一个重要香料品种,工业上主要由苯乙烯溴-羟基化、环氧化、加氢而制得,其中关键一步是溴-羟基化反应,这是在油-水两相中进行的亲电加成反应[1,2]。本文根据前人的工作[1,2,3],在反应中加进了不同分子量的聚乙二醇,考察了它们对反应的影响,讨论了聚乙二醇的相转移催化行为。

关键词: 相转移催化, 聚乙二醇, 溴-羟基化, 苯乙烯

Abstract: Polyethylene glycol(PEG)is used as a phase transfer catalyst in the bromo-hydroxylationof styrene.Experimental results showed that the yield of β-blomo-α-hydroxyethylbenzeneand the reaction rate are enhanced by addition of PEG into the system, and the effectincreased remarkably with the increasing amount of sulfuric acid. The maximum, yield ofβ-bromo-α-hydroxyethylbenzen is 92%. A possible mechanism is proposed.

Key words: phase transfer catalysis, polyethylene glycol, styrene, bromo-hydioxylation

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