中华医学超声杂志

应用化学 ›› 2010, Vol. 27 ›› Issue (03): 353-357.DOI: 10.3724/SP.J.1095.2010.90208

• 研究论文 • 上一篇    下一篇

银掺杂聚L-天冬氨酸修饰电极的制备及对肾上腺素的测定

陈高礼,马伟,孙登明   

  1. (淮北煤炭师范学院化学与材料科学学院 淮北 235000)
  • 收稿日期:2009-03-30 修回日期:2009-06-01 出版日期:2010-03-10 发布日期:2010-03-10
  • 通讯作者: 孙登明，男，教授; E-mail:sundengming@126.com; 研究方向：电分析化学
  • 基金资助:
    安徽省重点科研计划基金(07020203011)安徽省高校省级自然科学研究重点基金(KJ2008A122)资助项目

Preparation of Silver Doped Poly (L-Aspartic Acid) Modified Electrode and Its Determination for Epinephrine

CHEN Gao-Li, MA Wei, SUN Deng-Ming*   

  1. (School of Chemistry and Materials Science,Huaibei Coal Normal College,Huaibei 235000)
  • Received:2009-03-30 Revised:2009-06-01 Published:2010-03-10 Online:2010-03-10

PDF

1370

被引次数

36 | 12

摘要：

利用循环伏安法，研究了银和L-天冬氨酸在玻碳电极表面电化学聚合的条件，制备了银掺杂聚L-天冬氨酸修饰电极，并研究了肾上腺素在该修饰电极上的电化学行为，建立了循环伏安法测定肾上腺素的新方法。在pH=3.5的磷酸盐缓冲溶液中，扫描速率为50 mV/s时，肾上腺素在修饰电极上产生一对氧化还原峰，Epa=0.447 V，Epc=0.387 V。用循环伏安法测定时，氧化峰电流与肾上腺素浓度分别在8.0×10-8~1.0×10-5 mol/L和1.0×10-5~1.0×10-4 mol/L范围内呈良好的线性关系，检出限为8.0×10-9 mol/L。

关键词: 肾上腺素, L-天冬氨酸, 银掺杂, 修饰电极, 循环伏安法

Abstract:

The silver doped poly(L-aspartic acid) modified electrode was prepared by cyclic voltammetric method, and the voltammetric behavior of epinephrine and cyclic voltammetric method determination of epinephrine were studied at the silver doped poly(L-aspartic acid) modified electrode. In pH3.5 phosphate buffer solution, the peak potential of epinephrine were 0.447V of Epa and 0.387 V of Epc (νs Ag/AgCl) at the scan rate 50 mV/s. The linear range for the determination of epinephrine were 8.0×10-8~1.0×10-5 mol/L and 1.0×10-5~1.0×10-4 mol/L. The detection limit was 8.0×10-9 mol/L. This method was applied to the determination of epinephrine in drug and urine with satisfactory results.

Key words: epinephrine, L-aspartic acid, silver doped, modified electrode, cyclic voltammetry

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