中华医学超声杂志

应用化学 ›› 2011, Vol. 28 ›› Issue (02): 240-244.DOI: 10.3724/SP.J.1095.2011.00219

• 研究论文 • 上一篇    

纳米金-二氧化钛纳米针修饰电极用于氯霉素检测

辛欣,魏南南,陆天虹,杜江燕*   

  1. (江苏省生物功能材料重点实验室，南京师范大学化学与环境科学学院 南京 210046)
  • 收稿日期:2010-04-15 修回日期:2010-07-20 出版日期:2011-02-10 发布日期:2011-02-10
  • 通讯作者: 杜江燕,教授; E-mail:dujiangyan@njnu.edu.cn; 办公电话:025-85891651; 传真:025-85891767; 研究方向：生物电化学
  • 基金资助:
    国家自然科学重点基金(20833006)资助项目

Application of Gold-nanoparticle-doped Titanium Dioxide Nanoneedle Modified Electrode for Detection of Chloramphenicol

XIN Xin, WEI Nan-Nan, LU Tian-Hong, DU Jiang-Yan*   

  1. (Jiangsu Key Laboratory of Biofunctional Materials,College of Chemistry and Environmental Science,Nanjing Normal University,Nanjing 210046)
  • Received:2010-04-15 Revised:2010-07-20 Published:2011-02-10 Online:2011-02-10

PDF

1493

被引次数

9 | 4

摘要：

将金胶-TiO2纳米针修饰玻碳(Au-TiO2/GC)电极用于对氯霉素(CAP)浓度的电化学测定。 结果表明，在0.1 mol/L pH=7.0的磷酸盐缓冲溶液(PBS)体系中，CAP在Au-TiO2/GC电极上有较好的电化学响应，CAP浓度在8.0×10-7～1.0×10-4 mol/L范围内，峰电流与其浓度呈良好的线性关系，检出限为7.8×10-8 mol/L。 并对氯霉素滴眼液中CAP浓度进行了检测，发现该方法有高的检测灵敏度、好的重复性和抗干扰性，且操作简便、成本低廉。

关键词: 电分析, 玻碳电极, 金胶, TiO2, 氯霉素

Abstract:

A gold nanoparticle-doped titanium dioxide nanoneedle modified glass carbon(Au-TiO2/GC) electrode was used for the electrochemical detection of the concentration of chloramphenicol(CAP). The results indicated that the Au-TiO2/GC electrode shows good electrochemical response for CAP in 0.1 mol/L PBS at pH=7.0. A linear relationship between the peak current and the concentration of CAP lies in the range of 8.0×10-7～1.0×10-4 mol/L with a detection limit of 7.8×10-8 mol/L. This method was applied to the detection of CAP concentration of CAP in eyedrop. It was found that this method has the high detection sensitivity, good reproducibility and ante-interference.

Key words: electroanalysis, glass carbon electrode, gold gel, titanium dioxide, chloramphenicol

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