生物遗传资源保藏技术与生物安全材料的研究进展

doi:10.19894/j.issn.1000-0518.210056

摘要/Abstract

摘要： 生物遗传资源是人类赖以生存的物质基础,其保藏与利用是国家战略的重要组成部分。尤其是随着医疗与科技水平的提升,人类遗传资源的安全保藏、规范利用引起了我国高度的重视,并颁布了《中华人民共和国人类遗传资源管理条例》。然而,当前生物遗传资源的保藏技术存在标准化难、安全性存疑的问题。本文梳理了几类主要生物遗传资源保藏技术的发展历史、保藏难点和相关生物安全材料的应用情况,并总结了前沿材料对各类遗传资源保藏的最新研究进展,以期为未来开发标准化、生物安全化的遗传资源保藏技术提供全面信息和有力支撑。

关键词: 生物遗传资源, 保藏技术, 生物安全材料, 细胞冻存, 保护剂

Abstract: Biological genetic resources are the material basis for human survival, and their long-term preservation and utilization also play an important role in national strategy. Especially with the improvement of medical research, the safe preservation and standardized utilization of human genetic recourses have attracted great attention in our nation, and the Regulations of the People′s Republic of China on Administration of Human Genetic Resources was promulgated simultaneously. However, the difficulty of standardization and safety problems have limited the genetic resource preservation technology. In this review, we clarify the development history, the difficulty, and the protection materials of current preservation technologies, and summarize the latest research progress of novel biomaterials on various kinds of genetic resources preservation. This review will provide a comprehensive information and strong support to exploit the safe and standardized genetic preservation technologies.

Key words: Biological genetic resources, Preservation technology, Biosafety materials, Cell cryopreservation, Protectants

中图分类号:

O632

马一鸣, 周晓, 田云青, 杨静, 张雷. 生物遗传资源保藏技术与生物安全材料的研究进展[J]. 应用化学, 2021, 38(5): 482-497.

MA Yi-Ming, ZHOU Xiao, TIAN Yun-Qing, YANG Jing, ZHANG Lei. Research Progress of Biosafety Materials and Technology of Genetic Resource Preservation[J]. Chinese Journal of Applied Chemistry, 2021, 38(5): 482-497.

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