Chinese Journal of Applied Chemistry ›› 2024, Vol. 41 ›› Issue (7): 966-975.DOI: 10.19894/j.issn.1000-0518.230394
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Ling-Dong LI1,2(), Song-Wei ZHANG2, Wei-Lun ZHANG2, Peng-Fei LIU2, Jiang-Jiming YU2, Hao ZHOU2
Received:
2023-12-19
Accepted:
2024-05-15
Published:
2024-07-01
Online:
2024-08-03
Contact:
Ling-Dong LI
About author:
lild@dlut.edu.cnSupported by:
CLC Number:
Ling-Dong LI, Song-Wei ZHANG, Wei-Lun ZHANG, Peng-Fei LIU, Jiang-Jiming YU, Hao ZHOU. Synthesis of Side Chain Derived Quaternary Ammonium N-Chloramines for Antibacterial Applications[J]. Chinese Journal of Applied Chemistry, 2024, 41(7): 966-975.
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URL: http://yyhx.ciac.jl.cn/EN/10.19894/j.issn.1000-0518.230394
Bacteria | Compound | c(active chloramine)/ ( mmol·L-1) | 5 min contact time | 10 min contact time | ||
---|---|---|---|---|---|---|
KR/% | KL | KR/% | KL | |||
S.aureus | 1a | 0.56 | 22.61±2.22 | 0.11±0.01 | 62.33±3.32 | 0.42±0.04 |
10a a | 0 | 0 | 0 | 0 | 0 | |
10a | 0.56 | 25.21±1.39 | 0.13±0.01 | 63.71±1.39 | 0.44±0.02 | |
11a a | 0 | 0 | 0 | 0 | 0 | |
11a | 0.56 | 30.47±2.77 | 0.16±0.01 | 77.29±4.99 | 0.64±0.10 | |
12a a | 0 | 0 | 0 | 0 | 0 | |
12a | 0.56 | 36.56±4.99 | 0.20±0.06 | 91.41±1.94 | 1.07±0.09 | |
13a a | 0 | 0 | 0 | 0 | 0 | |
13a | 0.56 | 36.33±1.11 | 0.19±0.01 | 69.53±2.49 | 0.52±0.03 | |
11a b | 0 | 0 | 0 | 0 | 0 | |
11b | 0.56 | 20.5±0.07 | 0.10±0.01 | 70.86±1.20 | 0.54±0.02 | |
14a b | 0 | 0 | 0 | 0 | 0 | |
14b | 0.56 | 100 | 6.92 | 100 | 6.92 | |
E.coli | 1a | 0.56 | 48.37±1.96 | 0.29±0.02 | 84.97±3.27 | 0.82±0.09 |
10a a | 0 | 0 | 0 | 0 | 0 | |
10a | 0.56 | 60.13±5.23 | 0.40±0.04 | 96.73±0.65 | 1.49±0.08 | |
11a a | 0 | 0 | 0 | 0 | 0 | |
11a | 0.56 | 62.09±2.61 | 0.42±0.03 | 99.35±0.65 | 2.18±0.00 | |
12a a | 0 | 0 | 0 | 0 | 0 | |
12a | 0.56 | 66.67±3.27 | 0.48±0.04 | 100±0.00 | 6.49 | |
13a a | 0 | 0 | 0 | 0 | 0 | |
13a | 0.56 | 57.52±3.92 | 0.37±0.04 | 94.12±1.31 | 1.23±0.09 | |
11a b | 0 | 0 | 0 | 0 | 0 | |
11b | 0.56 | 54.1±2.04 | 0.34±0.02 | 99.49±0.51 | 2.29±0.00 | |
14a b | 0 | 0 | 0 | 0 | 0 | |
14b | 0.56 | 100 | 6.59 | 100 | 6.59 |
Table 1 Antibacterial activity of N-chloramines 10-14
Bacteria | Compound | c(active chloramine)/ ( mmol·L-1) | 5 min contact time | 10 min contact time | ||
---|---|---|---|---|---|---|
KR/% | KL | KR/% | KL | |||
S.aureus | 1a | 0.56 | 22.61±2.22 | 0.11±0.01 | 62.33±3.32 | 0.42±0.04 |
10a a | 0 | 0 | 0 | 0 | 0 | |
10a | 0.56 | 25.21±1.39 | 0.13±0.01 | 63.71±1.39 | 0.44±0.02 | |
11a a | 0 | 0 | 0 | 0 | 0 | |
11a | 0.56 | 30.47±2.77 | 0.16±0.01 | 77.29±4.99 | 0.64±0.10 | |
12a a | 0 | 0 | 0 | 0 | 0 | |
12a | 0.56 | 36.56±4.99 | 0.20±0.06 | 91.41±1.94 | 1.07±0.09 | |
13a a | 0 | 0 | 0 | 0 | 0 | |
13a | 0.56 | 36.33±1.11 | 0.19±0.01 | 69.53±2.49 | 0.52±0.03 | |
11a b | 0 | 0 | 0 | 0 | 0 | |
11b | 0.56 | 20.5±0.07 | 0.10±0.01 | 70.86±1.20 | 0.54±0.02 | |
14a b | 0 | 0 | 0 | 0 | 0 | |
14b | 0.56 | 100 | 6.92 | 100 | 6.92 | |
E.coli | 1a | 0.56 | 48.37±1.96 | 0.29±0.02 | 84.97±3.27 | 0.82±0.09 |
10a a | 0 | 0 | 0 | 0 | 0 | |
10a | 0.56 | 60.13±5.23 | 0.40±0.04 | 96.73±0.65 | 1.49±0.08 | |
11a a | 0 | 0 | 0 | 0 | 0 | |
11a | 0.56 | 62.09±2.61 | 0.42±0.03 | 99.35±0.65 | 2.18±0.00 | |
12a a | 0 | 0 | 0 | 0 | 0 | |
12a | 0.56 | 66.67±3.27 | 0.48±0.04 | 100±0.00 | 6.49 | |
13a a | 0 | 0 | 0 | 0 | 0 | |
13a | 0.56 | 57.52±3.92 | 0.37±0.04 | 94.12±1.31 | 1.23±0.09 | |
11a b | 0 | 0 | 0 | 0 | 0 | |
11b | 0.56 | 54.1±2.04 | 0.34±0.02 | 99.49±0.51 | 2.29±0.00 | |
14a b | 0 | 0 | 0 | 0 | 0 | |
14b | 0.56 | 100 | 6.59 | 100 | 6.59 |
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