Identification of Chemical Constituents of American Ginseng Fruit Pedicels by Ultra-performance Liquid Chromatography  Quadrupole Time-of-Flight Mass Spectrometry

doi:10.19894/j.issn.1000-0518.200391

Chinese Journal of Applied Chemistry ›› 2021, Vol. 38 ›› Issue (3): 256-270.DOI: 10.19894/j.issn.1000-0518.200391

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Identification of Chemical Constituents of American Ginseng Fruit Pedicels by Ultra-performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

LI Le¹, TAN Lu-Ying¹, WANG Cai-Xia¹, LI Kun², LI Ping-Ya¹, LIU Jin-Ping¹, LIU Yun-He^1*

¹Jilin University Natural Medicine Research Center, School of Pharmacy, Jilin University, Changchun 130021, China
²Jilin Zixin Pharmaceutical Research Co., Ltd., Changchun 130021, China

Received:2020-12-24 Accepted:2021-01-21 Published:2021-03-01 Online:2021-05-01
Supported by:
Graduate Innovation Fund of Jilin University (No.101832020CX316)

Abstract

Abstract: An ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF-MS) technology was used to quickly and comprehensively analyze the chemical components of American ginseng fruit pedicels, UNIFI natural product analysis platform was then applied to compare the retention time of each component, accurate molecular mass and fragment ion information. There are 101 chemical components identified or preliminary identified, mainly including 74 triterpene saponins, 5 steroids, 11 organic acids and organic acid esters. The results show that American ginseng fruit pedicels are rich in ginsenosides and should be used as natural resources of saponins. This study can provide a theoretical basis for the rational development and application of American ginseng fruit pedicels resources.

Key words: American ginseng, Fruit pedicels, Ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry, Chemical composition

CLC Number:

O629

LI Le, TAN Lu-Ying, WANG Cai-Xia, LI Kun, LI Ping-Ya, LIU Jin-Ping, LIU Yun-He. Identification of Chemical Constituents of American Ginseng Fruit Pedicels by Ultra-performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry[J]. Chinese Journal of Applied Chemistry, 2021, 38(3): 256-270.

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Identification of Chemical Constituents of American Ginseng Fruit Pedicels by Ultra-performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

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