Chinese Journal of Applied Chemistry ›› 2020, Vol. 37 ›› Issue (9): 1062-1068.DOI: 10.11944/j.issn.1000-0518.2020.09.200076

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Preparation and Application of Catechin-Silver Nanocomposites

XING Yayana,b, SHI Yuzhea,b, DENG Shixiana,b, ZHAO Baihana,b, LIU Zhiguoa,b*   

  1. aCollege of Chemistry,Chemical Engineering and Resource Utilization,Northeast Forestry University,Harbin 150040,China;
    bKey Laboratory of Forest Plant Ecology,Ministry of Education,Northeast Forestry University,Harbin 150040,China
  • Received:2020-03-17 Published:2020-09-01 Online:2020-09-09
  • Contact: LIU Zhiguo, professor; Tel:0451-82192224;; Research interests:phytochemistry
  • Supported by:
    Supported by the Fundamental Research Funds for the Central Universities(No.2572018CT01) and the Natural Science Fund of Heilongjiang Province(No.LH2019B001)

Abstract: In this study, we explored a one-step hydrothermal synthesis method to synthesize catechin-silver nanocomposite wherein catechin was acted as the reduction agent and protection agent. The ultrviolet-visible (UV-Vis) and Fourier transform infrared spectroscopy(FTIR) measurements confirm that the obtained nanomaterials are catechin-capped Ag nanoparticles. Transmission electron microscopy(TEM) and X-ray diffraction(XRD) results indicate that the average diameter of the Ag nanoparticles is 22.7 nm, and the Ag nanoparticles have the face centered cubic crystal structure. We further studied the antibacterial activity of catechin-silver nanoparticles. The results of bacteriostatic experiments reveal that the catechin-silver nanoparticles have a strong inhibitory effect on E.coli, S.aureus and C.albicans. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) for C.albicans is 19.63 and 39.26 μg/mL, respectively. The inhibitory activity of catechin-silver nanoparticles can be attributed to the continuous release of Ag+ from their surface. The catechin-silver nanocomposite is expected to be used in long-acting antibacterial agents.

Key words: catechin, silver nanocomposite, antibacterial activity